DNA methylation in plants: mechanisms and tools for targeted manipulation
J Gallego‐Bartolomé - New Phytologist, 2020 - Wiley Online Library
… tools for locus-specific manipulation of DNA methylation. These can also … DNA methylation
in plants, focusing on recent advances in the development of tools for its targeted manipulation…
in plants, focusing on recent advances in the development of tools for its targeted manipulation…
Gene-specific targeting of DNA methylation in the mammalian genome
A Urbano, J Smith, RJ Weeks, A Chatterjee - Cancers, 2019 - mdpi.com
… DNA methylation and transcription has been difficult thus far. Fortunately, the recent development
of targeted tools for manipulating DNA methylation … regulation of DNA methylation in …
of targeted tools for manipulating DNA methylation … regulation of DNA methylation in …
Technologies for targeting DNA methylation modifications: basic mechanism and potential application in cancer
J Wang, J Yang, D Li, J Li - Biochimica et Biophysica Acta (BBA)-Reviews …, 2021 - Elsevier
… manipulating gene epigenetic alterations in a more specific and efficient method. In this review,
we described different targeting DNA methylation … understanding of these targeting tools, …
we described different targeting DNA methylation … understanding of these targeting tools, …
DNA methylation and de-methylation using hybrid site-targeting proteins
… DNA methylation and transcription. Here, we focus on recent advances in targeted DNA
methylation … they have provided into how forcible methylation and demethylation govern gene …
methylation … they have provided into how forcible methylation and demethylation govern gene …
Harnessing targeted DNA methylation and demethylation using dCas9
… , implementation, and targeting specificity. Effective targeted DNA methylation editing will
continue … strategies, considerations, and future directions for targeted DNA methylation editing. …
continue … strategies, considerations, and future directions for targeted DNA methylation editing. …
Targeted DNA methylation in vivo using an engineered dCas9-MQ1 fusion protein
… of a systematic understanding of DNA methylation and the dynamic changes of … efficient
targeted DNA methylation by fusing inactive Cas9 (dCas9) with an engineered prokaryotic DNA …
targeted DNA methylation by fusing inactive Cas9 (dCas9) with an engineered prokaryotic DNA …
Reshaping the Landscape of the Genome: Toolkits for Precise DNA Methylation Manipulation and Beyond
C Zhu, Z Hao, D Liu - JACS Au, 2023 - ACS Publications
… and demethylation processes, an intuitive way to enable targeted manipulation of DNA
methylation is by fusing DNBPs with DNMTs or TETs. In such a fusion protein system, the …
methylation is by fusing DNBPs with DNMTs or TETs. In such a fusion protein system, the …
Repurposing the CRISPR-Cas9 system for targeted DNA methylation
… methylation of a larger part of the promoter. DNA methylation activity was specific for the
targeted … that directed DNA methylation of a wider promoter region of the target loci IL6ST and …
targeted … that directed DNA methylation of a wider promoter region of the target loci IL6ST and …
CRISPR-dCas9-based targeted manipulation of DNA methylation in plants
B Ghoshal, J Gardiner - CRISPR-Cas Methods: Volume 2, 2021 - Springer
… protocol for targeted manipulation of DNA methylation by … lab for the targeted manipulation
of DNA methylation in Arabidopsis… further study into the function of DNA methylation in plants. …
of DNA methylation in Arabidopsis… further study into the function of DNA methylation in plants. …
Large-scale manipulation of promoter DNA methylation reveals context-specific transcriptional responses and stability
… These artificial epigenome modification techniques allow targeted interrogation of
whether DNA methylation correlates with, or is causative for, transcriptional repression. Their …
whether DNA methylation correlates with, or is causative for, transcriptional repression. Their …
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