… It remains unclear how DNA methylation affects LSC differentiation and tumorigenesis. …
DNA methylation during the LSC differentiation process. We hypothesized that DNA methylation “…

… a promising target for diagnostic and … of DNA methylation is based on the sodium
bisulfite-based fine mapping of individual CpG dinucleotides, the preferred target of DNA methylation …

… Thus, it is possible to combine drugs that target DNA methylation with cytotoxic or cytostatic
drugs to achieve better tumor response. An advantage of using a combination of the drugs is …

… Methylation of DNA is a biochemical modification that can … of abnormalities in DNA methylation
may therefore restore the … rationale for targeting aberrant methylation in cancer therapy …

… also a method used for regulating genome-wide DNA methylation. However, techniques for
manipulating DNA methylation targeting only specific genomic loci are not well established, …

… the CRISPR technique to target DNA methylation to a specific … DNA sequence targeted
by sgRNA molecules, but due to the lack of endonuclease activity does not cleave the DNA…

… that targeted epigenetic manipulations confined to … the targeted epigenetic manipulation
of behaviorally allocated neuronal ensembles. We showed that the expression levels of a DNA …

… DNA methylation serves as a cellular memory system and how it is dynamically regulated
through the action of the DNA … H3K9 methylation at chromosomal MBD1 target sequences for …

… increase the DNA methylation state … DNA methylation into pericentromeres of early mouse
embryos by expressing TALE-SssI fusion protein and a method for detecting DNA methylation…

… gene-targeted and whole-genome sequencing studies that have brought DNA methylation
to … experimental findings regarding distinct manipulations of DNA methylation and their effect …