… in DNA methylation may therefore restore the tumor-suppressive function of these genes and
provide a novel approach to cancer therapy. Two … aberrant methylation in cancer therapy is …

… with the DNA methylation machinery is a potentially powerful approach to cancer therapy, it
is … , to properly utilize agents targeting the DNA methylation machinery in anticancer therapy. …

… the therapeutic implications of DNA methylation. First, because the level of DNA methyltransferase …
is one determinant of the pattern of DNA methylation, partial inhibition of DNA methyl- …

In this review, we discuss the potential pharmacological targeting of a set of powerful
epigenetic mechanisms: DNA methylation control systems in the central nervous system (CNS). …

… of DNA methylation in rheumatoid arthritis and indicate its potential therapeutic implications.
… In this review we aim to collate the current knowledge on DNA methylation in autoimmunity …

… In this review, we focus on the implications of epigenetic alterations such as DNA
methylation in predicting the efficacy of chemotherapeutic drugs in the treatment of cancer. …

… DNA, and it comprises a mechanism through which gene–environment interactions could
occur. Its mechanisms include DNA methylation… state of DNA methylation studies related to OA …

… attracted significant attention recently and DNA methylation inhibitors are being tested as …
clear implications on the therapeutic use of agents targeting the DNA methylation machinery…

DNA methylation refers to a heritable alteration in the pattern of gene expression that is
regulated by a mechanism specifically not owing to changes in the primary nucleotide sequence. …

… therapeutic targets. In this review, we describe the current state of knowledge on the different
classes of DNA methylation “… This review focuses on the known families of DNA methylation …