[HTML][HTML] Tissue-specific DNA methylation is conserved across human, mouse, and rat, and driven by primary sequence conservation

J Zhou, RL Sears, X Xing, B Zhang, D Li… - BMC genomics, 2017 - Springer
… the tissue-specific DNA methylation patterns of rat against those of mouse and human …
three shared tissue types. We confirmed that tissue-specific differentially methylated regions …

[HTML][HTML] Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context

BC Christensen, EA Houseman, CJ Marsit… - PLoS …, 2009 - journals.plos.org
… underlying interindividual differences in tissue specific methylation that lead us to an
understanding of the nature of the relationships that govern these crucial tissue specific differences. …

Tissue-specific differences in DNA methylation in various mammals

MA Gama-Sosa, RM Midgett, VA Slagel… - … et Biophysica Acta (BBA …, 1983 - Elsevier
… of methylation of their cytosine residues. Several similarities in the patterns of tissue-specific
DNA methylation … Compared to most other types of DNA examined, brain and thymus DNAs …

Tissue specific DNA methylation of CpG islands in normal human adult somatic tissues distinguishes neural from non-neural tissues

S Ghosh, AJ Yates, MC Frühwald, JC Miecznikowski… - Epigenetics, 2010 - Taylor & Francis
… human somatic tissues and fewer still have studied the same sets of tissues from multiple …
to study tissue specific methylation patterns in a set of twelve human tissues collected from …

[HTML][HTML] Tissue-specific DNA methylation variability and its potential clinical value

RH Miller, CA Pollard, KR Brogaard, AC Olson… - Frontiers in …, 2023 - frontiersin.org
… We believe that assessing DNA methylation in this way will offer improved predictive
power for many disease states because it is focused on more widespread alterations to gene …

[HTML][HTML] Tissue-independent and tissue-specific patterns of DNA methylation alteration in cancer

Y Chen, CE Breeze, S Zhen, S Beck… - Epigenetics & …, 2016 - Springer
DNA methylation patterns of ten types of fetal tissue, in addition to matched normal-cancer
data for corresponding tissue … the level of aberrant cancer DNA methylation in gene promoters …

[HTML][HTML] Genome-wide survey reveals dynamic widespread tissue-specific changes in DNA methylation during development

P Liang, F Song, S Ghosh, E Morien, M Qin… - BMC genomics, 2011 - Springer
DNA methylation has tissue specificity, that demethylation has a prominent role in tissue
differentiation, and that DNA methylation … changes in DNA methylation during development are …

DNA methylation and gene activity.

H Cedar - Cell, 1988 - europepmc.org
… The above experiments support a relatively simple model to explain the role of DNA
methylation in vivo. Most tissue-specific genes are methylated. The methyl groups may generate a …

[HTML][HTML] DNA methylome profiling of human tissues identifies global and tissue-specific methylation patterns

K Lokk, V Modhukur, B Rajashekar, K Märtens, R Mägi… - Genome biology, 2014 - Springer
… Our aim was to describe the general patterns of globally conserved and tissue-specific
DNA methylation with functional consequences in gene regulation. Using the high-density …

[HTML][HTML] Tissue specific DNA methylation in normal human breast epithelium and in breast cancer

A Avraham, SS Cho, R Uhlmann, ML Polak… - PloS one, 2014 - journals.plos.org
… frequent DNA methylation variation among normal tissues are also differentially methylated
and … Accordingly, the identification of tissue-specific epigenetic regulation may throw light on …