Sensitivity of transcription factors to DNA methylation
… Although DNA methylation has long been thought to repress TF binding, a more recent …
inhibit DNA methylation. Here, we review the possible scenarios by which DNA methylation and …
inhibit DNA methylation. Here, we review the possible scenarios by which DNA methylation and …
Transcription factors as readers and effectors of DNA methylation
… also interact with methylated DNA. The … methylation-dependent transcription factor–DNA
interactions are important stepping stones towards a mechanistic understanding of methylation-…
interactions are important stepping stones towards a mechanistic understanding of methylation-…
Cross-talk between site-specific transcription factors and DNA methylation states
A Blattler, PJ Farnham - Journal of Biological Chemistry, 2013 - ASBMB
… Because DNA methylation is reversible, there is … by DNA-binding transcription factors. We
discuss several models that, by incorporating sequence motifs, CpG density, and methylation …
discuss several models that, by incorporating sequence motifs, CpG density, and methylation …
DNA methylation presents distinct binding sites for human transcription factors
… Because our goal was to identify DNA methylation-dependent binding activity, we developed
a competition assay on a protein microarray to identify TFs that prefer DNA motifs carrying …
a competition assay on a protein microarray to identify TFs that prefer DNA motifs carrying …
On how mammalian transcription factors recognize methylated DNA
BA Buck-Koehntop, PA Defossez - Epigenetics, 2013 - Taylor & Francis
… , DNA methylation regulates gene expression by repressing promoter activity. The repressive
effects of DNA methylation on the … Citation 12 DNA methylation can prevent transcriptional …
effects of DNA methylation on the … Citation 12 DNA methylation can prevent transcriptional …
Emerging concept in DNA methylation: role of transcription factors in shaping DNA methylation patterns
… In the current review, we will focus our discussion on the role of transcription factors and
signaling pathways in regulating DNA methylation profiles, and their changes in response to …
signaling pathways in regulating DNA methylation profiles, and their changes in response to …
Role of DNA methylation in modulating transcription factor occupancy
MT Maurano, H Wang, S John, A Shafer, T Canfield… - Cell reports, 2015 - cell.com
… abrogation of DNA methylation. The small fraction of sites that show methylation-dependent …
Our results suggest that DNA methylation is not a primary groundskeeper of genomic TF …
Our results suggest that DNA methylation is not a primary groundskeeper of genomic TF …
Dnmt3/transcription factor interactions as crucial players in targeted DNA methylation
E Hervouet, FM Vallette, PF Cartron - Epigenetics, 2009 - Taylor & Francis
… sequence for DNA methylation of Dnmt3a is increased in presence of c-myc. By … transcription
factor array spotted with 103 transcription factors, we next identified 79 transcription factors …
factor array spotted with 103 transcription factors, we next identified 79 transcription factors …
Quantitative analysis of the DNA methylation sensitivity of transcription factor complexes
… To quantitatively assess the effects of DNA methylation on TF binding, we developed a
method in which a methylated library (Lib-M) and an unmethylated library (Lib-U) containing a …
method in which a methylated library (Lib-M) and an unmethylated library (Lib-U) containing a …
DNA methylation and the regulation of gene transcription
JT Attwood, RL Yung, BC Richardson - Cellular and Molecular Life …, 2002 - Springer
… cytosine bases leads to the inaccessibility of DNA regulatory elements to their transcription
factors by a number of mechanisms. Our understanding of DNA methylation has advanced …
factors by a number of mechanisms. Our understanding of DNA methylation has advanced …
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