Emerging concept in DNA methylation: role of transcription factors in shaping DNA methylation patterns
… In the current review, we will focus our discussion on the role of transcription factors and
signaling pathways in regulating DNA methylation profiles, and their changes in response to …
signaling pathways in regulating DNA methylation profiles, and their changes in response to …
Sensitivity of transcription factors to DNA methylation
… Together with the observation of a strong anti-correlation between TF binding and DNA
methylation patterns genome wide, a new actively discussed hypothesis has emerged where …
methylation patterns genome wide, a new actively discussed hypothesis has emerged where …
Cross-talk between site-specific transcription factors and DNA methylation states
A Blattler, PJ Farnham - Journal of Biological Chemistry, 2013 - ASBMB
… ), and there is much interest in understanding the mechanisms by which DNA methylation
patterns are established. In this review, we focus on regulation of methylation patterns at …
patterns are established. In this review, we focus on regulation of methylation patterns at …
Genomic patterns and context specific interpretation of DNA methylation
T Baubec, D Schübeler - Current opinion in genetics & development, 2014 - Elsevier
… that dynamics in DNA methylation coincide with changes in regulatory activity and that
transcription factors play an important role in shaping methylation patterns. This tightly links …
transcription factors play an important role in shaping methylation patterns. This tightly links …
Transcription factors as readers and effectors of DNA methylation
… in vivo, although further in vivo genome-wide characterization of TF binding patterns and
high-resolution DNA methylation analyses are needed to strengthen the evidence base. The …
high-resolution DNA methylation analyses are needed to strengthen the evidence base. The …
Pioneer transcription factors are associated with the modulation of DNA methylation patterns across cancers
RB Lemma, T Fleischer, E Martinsen, M Ledsaak… - Epigenetics & …, 2022 - Springer
… hypothesised that aberrant methylation patterns could be controlled by the binding of specific
transcription factors (TFs) across cancer types. By combining DNA methylation arrays and …
transcription factors (TFs) across cancer types. By combining DNA methylation arrays and …
DNA methylation patterns and epigenetic memory
A Bird - Genes & development, 2002 - genesdev.cshlp.org
… of gene expression patterns are DNA-binding transcription factors that choose genes for
transcriptional activation or repression by recognizing the sequence of DNA bases in their …
transcriptional activation or repression by recognizing the sequence of DNA bases in their …
[HTML][HTML] DNA methylation patterns of transcription factor binding regions characterize their functional and evolutionary contexts
M Rimoldi, N Wang, J Zhang… - Genome …, 2024 - genomebiology.biomedcentral.com
… To investigate multiple coexisting DNA methylation patterns, we derived the methylation
profiles of extended TFBRs using generalized linear model regression and clustering with the …
profiles of extended TFBRs using generalized linear model regression and clustering with the …
Establishment of de novo DNA methylation patterns: transcription factor binding and deoxycytidine methylation at CpG and non-CpG sequences in an integrated …
M Toth, U Müller, W Doerfler - Journal of molecular biology, 1990 - Elsevier
… Subsequently, methylation further spreads to neighboring regions, and the patterns of
complexed transcription factors are altered. Evidence has been adduced that DNA methylation at …
complexed transcription factors are altered. Evidence has been adduced that DNA methylation at …
DNMTs and impact of CpG content, transcription factors, consensus motifs, lncRNAs, and histone marks on DNA methylation
… DNA methyltransferases (DNMTs) play an essential role in DNA methylation and transcriptional
… elements, modulate the dynamic DNA methylation patterns of embryonic and adult cells. …
… elements, modulate the dynamic DNA methylation patterns of embryonic and adult cells. …
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