… , aberrant DNA methylation patterns play a … DNA methylation is transitioning between,
rather than maintaining cellular states. This line of thinking raises the question how methylation …

… can alter gene expression profiles by influencing the binding affinities of transcription factors
or other proteins to DNA; that patterns of DNA methylation exist; and that these patterns vary …

… 3a), we observed an inverse methylation pattern with both T-cell cell lines being hypermethylated
(>90 percent, data not shown). However, for a number of genes such as c-maf, TCF7, …

… of transcriptional states 10,11 . This potential for inheritance coupled with the fact that DNA
methylation patterns … that other transcription factors are more sensitive to DNA methylation, in …

… Here we summarize the present understanding of DNA methylation in normal cells and …
Thus, determination of aberrant DNA methylation pattern could be used as an epigenetic …

… However, few studies have attempted to predict DNA methylation patterns. DNA methylation
occurs at C 5 cytosine positions, mainly in CpG loci. Some research has focused on CpG …

… faithful transfer of DNA methylation patterns during cell … transcription factors. Elife 2,
e00726 (2013). This paper reveals that a large number of transcription factors interact with DNA …

… suggests the association of DNA methylation with gene activity [11-… methylation patterns
during development must be elucidated. In this article the basic features of methylation patterns, …

… To test if cell-type-specific methylation patterns could similarly explain differential binding
of NRF1, we differentiated ES cells into neuronal progenitors and investigated NRF1 binding. …

… in DNA methylation patterns, we first had to examine the degree of variability in methylation
… We observed differential methylation in a number of transcription factors in lupus CD4 + T …