Transcription Factor Nrg1 Mediates Capsule Formation, Stress Response, and Pathogenesis in Cryptococcus neoformans

KL Cramer, QD Gerrald, CB Nichols, MS Price… - Eukaryotic …, 2006 - Am Soc Microbiol
neoformans transcription factors that are downstream … its response to stress and adapts to
the host environment. Here we identify one such transcription factor that is controlled by the C. …

Posttranslational, Translational, and Transcriptional Responses to Nitric Oxide Stress in Cryptococcus neoformans: Implications for Virulence

TA Missall, ME Pusateri, MJ Donlin, KT Chambers… - Eukaryotic …, 2006 - Am Soc Microbiol
… has not been studied in fungi, though transcriptional responses to RNS have been recently
… In this study, we examine the proteomic and transcriptional response of C. neoformans to …

Transcriptional regulation by protein kinase A in Cryptococcus neoformans

G Hu, BR Steen, T Lian, AP Sham, N Tam… - PLoS …, 2007 - journals.plos.org
… this may influence a UPR-like response to indirectly regulate transcription factors leading
to the observed transcriptional responses. In addition to transcriptional effects, a more direct …

HapX Positively and Negatively Regulates the Transcriptional Response to Iron Deprivation in Cryptococcus neoformans

…, S Saikia, G Hu, J Wang, CKY Fung, C D'Souza… - PLoS …, 2010 - journals.plos.org
… , in the transcriptional response to different iron sources, and in virulence. We also examined
the regulatory connections between Cir1, HapX and Rim101 at the transcriptional level. We …

The Cryptococcus neoformans Rim101 transcription factor directly regulates genes required for adaptation to the host

TR O'Meara, W Xu, KM Selvig… - … and cellular biology, 2014 - Am Soc Microbiol
neoformans Rim101 can act both as an activator and as a repressor of transcription, …
Moreover, we use in vivo RNA profiling to examine the transcriptional response of this pathogen to …

The transcriptional response of Cryptococcus neoformans to ingestion by Acanthamoeba castellanii and macrophages provides insights into the evolutionary …

LS Derengowski, HC Paes, P Albuquerque… - Eukaryotic …, 2013 - Am Soc Microbiol
… We have analyzed the transcriptional response by focusing on gene functional categories. …
Overall, our results show that the transcriptional responses of C. neoformans to the hostile …

The Cryptococcus neoformans capsule: a sword and a shield

TR O'Meara, JA Alspaugh - Clinical microbiology reviews, 2012 - Am Soc Microbiol
… of capsule is achieved through the transcriptional responses of multiple conserved
signaling pathways that have been coopted to regulate this C. neoformans-specific virulence-…

Opposing PKA and Hog1 signals control the post‐transcriptional response to glucose availability in Cryptococcus neoformans

D Banerjee, ALM Bloom… - Molecular …, 2016 - Wiley Online Library
The pathogenic fungus Cryptococcus neoformans must adapt to glucose‐limited conditions
in the lung and glucose replete conditions upon dissemination to the brain. We report that …

Cryptococcus neoformans, a fungus under stress

SM Brown, LT Campbell, JK Lodge - Current opinion in microbiology, 2007 - Elsevier
… The authors explored the transcriptional response to hypoxia in C. neoformans since the
organism is exposed to low oxygen conditions in the mammalian host tissues. This study is …

Regulatory mechanism of the atypical AP-1-like transcription factor Yap1 in Cryptococcus neoformans

YS So, S Maeng, DH Yang, H Kim, KT Lee, SR Yu… - Msphere, 2019 - Am Soc Microbiol
… However, the role of c-CRD and its regulatory mechanism remain unknown. Here, we report
that Yap1 is transcriptionally regulated in response to oxidative, osmotic, and membrane-…