The endosomal sorting complex required for transport machinery influences haem uptake and capsule elaboration in Cryptococcus neoformans

G Hu, M Caza, B Cadieux, E Bakkeren… - Molecular …, 2015 - Wiley Online Library
… fungus Cryptococcus neoformans. Previous work revealed that the ESCRT (endosomal sorting
complex required for transport) … Here, we further characterized the ESCRT machinery to …

Reciprocal functions of Cryptococcus neoformans copper homeostasis machinery during pulmonary infection and meningoencephalitis

TS Sun, X Ju, HL Gao, T Wang, DJ Thiele, JY Li… - Nature …, 2014 - nature.com
… fungus Cryptococcus neoformans, which can cause lethal meningoencephalitis in humans.
Cryptococcus … We speculate that there are uncharacterized Cu transport machineries in C. …

[PDF][PDF] Cryptococcus neoformans copper detoxification machinery is critical for fungal virulence

C Ding, RA Festa, YL Chen, A Espart, Ò Palacios… - Cell host & …, 2013 - cell.com
… Adaptation of Cryptococcus neoformans to mammalian hosts: integrated regulation of …
Selection of ura5 and ura3 mutants from the two varieties of Cryptococcus neoformans on 5-…

Unravelling Secretion in Cryptococcus neoformans: More than One Way to Skin a Cat

ML Rodrigues, JT Djordjevic - Mycopathologia, 2012 - Springer
… This was consistent with unimpeded laccase transport to the cell wall in the absence of …
machinery being transported by SEC6- and SEC14-1-dependent pathways, respectively. …

Transcriptional regulation by protein kinase A in Cryptococcus neoformans

G Hu, BR Steen, T Lian, AP Sham, N Tam… - PLoS …, 2007 - journals.plos.org
… the fungal pathogen Cryptococcus neoformans. Conversely, … in cell wall synthesis, transport
functions such as iron uptake, the … , heat shock, and transport showed abundant messages in …

Cryptococcus neoformans, a fungus under stress

SM Brown, LT Campbell, JK Lodge - Current opinion in microbiology, 2007 - Elsevier
Cryptococcus neoformans is a human fungal pathogen that survives exposure to stresses
during growth in the human host, including oxidative and nitrosative stress, high temperature, …

Iron and fungal pathogenesis: a case study with Cryptococcus neoformans

WH Jung, JW Kronstad - Cellular microbiology, 2008 - Wiley Online Library
… Cell surface reductases (Fre) reduce ferric to ferrous iron with subsequent transport mediated
neoformans exports reductants and may also employ melanin for ferric iron reduction. The …

The Sec1/Munc18 (SM) protein Vps45 is involved in iron uptake, mitochondrial function and virulence in the pathogenic fungus Cryptococcus neoformans

M Caza, G Hu, ED Nielson, M Cho, WH Jung… - PLoS …, 2018 - journals.plos.org
neoformans, iron from FeCl 3 or transferrin is transported by the high-affinity iron uptake
system composed of the iron permease Cft1 and the ferroxidase Cfo1 [9,10]. Indeed, deletion of …

Role of the ESCRT pathway in laccase trafficking and virulence of Cryptococcus neoformans

YD Park, SH Chen, E Camacho… - Infection and …, 2020 - Am Soc Microbiol
… required for transport (ESCRT) plays a crucial role in the transportation and degradation of
… for the transport of the virulence factor laccase to the cell wall in Cryptococcus neoformans. …

The novel J-domain protein Mrj1 is required for mitochondrial respiration and virulence in Cryptococcus neoformans

LC Horianopoulos, G Hu, M Caza, K Schmitt, P Overby… - MBio, 2020 - Am Soc Microbiol
… of complex III of the electron transport chain. The mrj1 mutants were … IMPORTANCE
Cryptococcus neoformans is the causative … neoformans. In this context, we characterized a unique …