… promoter methylation of previously unidentified target genes is a common abnormality in medulloblastomas–implications for tumor biology and potential clinical utility
MC Frühwald, MS O'Dorisio, Z Dai, SM Tanner… - Oncogene, 2001 - nature.com
… of the biological and clinical importance of promoter methylation in medulloblastomas and
… promoter methylation of the cell cycle regulator gene p15 INK4B , p16 INK4A and the tumor …
… promoter methylation of the cell cycle regulator gene p15 INK4B , p16 INK4A and the tumor …
MGMT promoter methylation in malignant gliomas
MJ Riemenschneider, ME Hegi, G Reifenberger - Targeted oncology, 2010 - Springer
… In malignant gliomas, however, the MGMT promoter methylation patterns are highly
heterogeneous from tumor to tumor and it is unknown which particular CpG sites or combinations …
heterogeneous from tumor to tumor and it is unknown which particular CpG sites or combinations …
DNA methylation in promoter region as biomarkers in prostate cancer
M Yang, JY Park - Cancer Epigenetics: Methods and Protocols, 2012 - Springer
… The reported frequencies of CDKN2A promoter methylation are inconsistent in prostate
tumors, ranging from 0 to 77% (25–27, 29–36). Perhaps these inconsistent results are due to …
tumors, ranging from 0 to 77% (25–27, 29–36). Perhaps these inconsistent results are due to …
Assessment of tumor suppressor promoter methylation in healthy individuals
DB Poduval, E Ognedal, Z Sichmanova, E Valen… - Clinical …, 2020 - Springer
… promoter methylation variation across the promoter … promoter methylation of tumor suppressor
genes fall into two main clusters defined by differences in genes regulating key biological …
genes fall into two main clusters defined by differences in genes regulating key biological …
Patterns of gene promoter methylation in squamous cell cancer of the head and neck
… the association of tumor suppressor gene promoter methylation in HNSCC … promoter
methylation of the p16 INK4a , DAP-kinase, E-Cadherin, and RASSF1A genes using methylation-…
methylation of the p16 INK4a , DAP-kinase, E-Cadherin, and RASSF1A genes using methylation-…
Genome-wide promoter analysis uncovers portions of the cancer methylome
… for basic research in tumor biology. [Cancer Res 2008;68(8):2661–70] … promoter methylation
in a limited number (n = 10–15 for tumors; n = 2–12 for normals) of various primary tumors …
in a limited number (n = 10–15 for tumors; n = 2–12 for normals) of various primary tumors …
Changes in correlation between promoter methylation and gene expression in cancer
… promoter methylation is considered a hallmark of cancer involved in silencing of tumor …
simple model of gene expression control by promoter methylation in cancer, and the precise …
simple model of gene expression control by promoter methylation in cancer, and the precise …
Genome-wide promoter methylation analysis in neuroblastoma identifies prognostic methylation biomarkers
… by promoter methylation, we first applied two independent genome-wide methylation …
makes an important contribution toward NB tumor biology by downregulating specific genes …
makes an important contribution toward NB tumor biology by downregulating specific genes …
Promoter methylation and the detection of breast cancer
J Brooks, P Cairns, A Zeleniuch-Jacquotte - Cancer Causes & Control, 2009 - Springer
… [24] looked at the promoter methylation of a panel of genes (RASSF1A, CCND2, TWIST, …
to the tumor. They found that promoter methylation was more frequently detected in tumor than …
to the tumor. They found that promoter methylation was more frequently detected in tumor than …
Promoter methylation profiling of 30 genes in human malignant melanoma
J Furuta, Y Umebayashi, K Miyamoto, K Kikuchi… - Cancer …, 2004 - Wiley Online Library
… methylation of a core region whose methylation blocks gene transcription when a study aims
for analysis of tumor… cannot be explained only by promoter methylation. Other groups have …
for analysis of tumor… cannot be explained only by promoter methylation. Other groups have …
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