… promoter methylation of previously unidentified target genes is a common abnormality in medulloblastomas–implications for tumor biology and potential clinical utility

MC Frühwald, MS O'Dorisio, Z Dai, SM Tanner… - Oncogene, 2001 - nature.com
… of the biological and clinical importance of promoter methylation in medulloblastomas and
promoter methylation of the cell cycle regulator gene p15 INK4B , p16 INK4A and the tumor

MGMT promoter methylation in malignant gliomas

MJ Riemenschneider, ME Hegi, G Reifenberger - Targeted oncology, 2010 - Springer
… In malignant gliomas, however, the MGMT promoter methylation patterns are highly
heterogeneous from tumor to tumor and it is unknown which particular CpG sites or combinations …

DNA methylation in promoter region as biomarkers in prostate cancer

M Yang, JY Park - Cancer Epigenetics: Methods and Protocols, 2012 - Springer
… The reported frequencies of CDKN2A promoter methylation are inconsistent in prostate
tumors, ranging from 0 to 77% (25–27, 29–36). Perhaps these inconsistent results are due to …

Assessment of tumor suppressor promoter methylation in healthy individuals

DB Poduval, E Ognedal, Z Sichmanova, E Valen… - Clinical …, 2020 - Springer
promoter methylation variation across the promoterpromoter methylation of tumor suppressor
genes fall into two main clusters defined by differences in genes regulating key biological

Patterns of gene promoter methylation in squamous cell cancer of the head and neck

M Hasegawa, HH Nelson, E Peters, E Ringstrom… - oncogene, 2002 - nature.com
… the association of tumor suppressor gene promoter methylation in HNSCC … promoter
methylation of the p16 INK4a , DAP-kinase, E-Cadherin, and RASSF1A genes using methylation-…

Genome-wide promoter analysis uncovers portions of the cancer methylome

MO Hoque, MS Kim, KL Ostrow, J Liu, GBA Wisman… - Cancer research, 2008 - AACR
… for basic research in tumor biology. [Cancer Res 2008;68(8):2661–70] … promoter methylation
in a limited number (n = 10–15 for tumors; n = 2–12 for normals) of various primary tumors

Changes in correlation between promoter methylation and gene expression in cancer

M Moarii, V Boeva, JP Vert, F Reyal - BMC genomics, 2015 - Springer
promoter methylation is considered a hallmark of cancer involved in silencing of tumor
simple model of gene expression control by promoter methylation in cancer, and the precise …

Genome-wide promoter methylation analysis in neuroblastoma identifies prognostic methylation biomarkers

A Decock, M Ongenaert, J Hoebeeck, K De Preter… - Genome biology, 2012 - Springer
… by promoter methylation, we first applied two independent genome-wide methylation
makes an important contribution toward NB tumor biology by downregulating specific genes …

Promoter methylation and the detection of breast cancer

J Brooks, P Cairns, A Zeleniuch-Jacquotte - Cancer Causes & Control, 2009 - Springer
… [24] looked at the promoter methylation of a panel of genes (RASSF1A, CCND2, TWIST, …
to the tumor. They found that promoter methylation was more frequently detected in tumor than …

Promoter methylation profiling of 30 genes in human malignant melanoma

J Furuta, Y Umebayashi, K Miyamoto, K Kikuchi… - Cancer …, 2004 - Wiley Online Library
methylation of a core region whose methylation blocks gene transcription when a study aims
for analysis of tumor… cannot be explained only by promoter methylation. Other groups have …