[HTML][HTML] Universal DNA methylation age across mammalian tissues
… , can be accurately estimated using DNA methylation profiles, the foundation of pan-… universal
pan-mammalian clocks, using 11,754 methylation arrays from our Mammalian Methylation …
pan-mammalian clocks, using 11,754 methylation arrays from our Mammalian Methylation …
Universal DNA methylation age across mammalian tissues
… in highly-conserved stretches of DNA, from 59 tissue-types derived … methylation profiles,
we constructed three age predictors, each with a single mathematical formula, termed universal …
we constructed three age predictors, each with a single mathematical formula, termed universal …
Universal DNA methylation age across mammalian tissues
Z Fei, K Raj, S Horvath - Innovation in Aging, 2021 - europepmc.org
… the methylation profiles of these age-related cytosines, we successfully constructed three
highly accurate universal … From the methylation profiles of these age-related cytosines, we …
highly accurate universal … From the methylation profiles of these age-related cytosines, we …
A multi-tissue age prediction model based on DNA methylation analysis
H Alsaleh, NA McCallum, DL Halligan… - Forensic Science …, 2017 - Elsevier
… universal DNA methylation markers across forensically relevant tissues. By using elastic net
regression, it was possible to identify 10 age-related (AR) DNA methylation … multi-tissue age …
regression, it was possible to identify 10 age-related (AR) DNA methylation … multi-tissue age …
[HTML][HTML] DNA methylation age of human tissues and cell types
S Horvath - Genome biology, 2013 - Springer
… I propose that DNA methylation age measures the cumulative effect of an epigenetic
maintenance system. This novel epigenetic clock can be used to address a host of questions in …
maintenance system. This novel epigenetic clock can be used to address a host of questions in …
[HTML][HTML] Multi-tissue DNA methylation age predictor in mouse
… We find that discrete DNA methylation changes correlate with chronological age and are
associated with biological functions. Based on these findings, we generated a multi-tissue age …
associated with biological functions. Based on these findings, we generated a multi-tissue age …
Trends in DNA methylation with age replicate across diverse human populations
… world; it is not known if age-related patterns of DNA methylation at these loci are similar across
… genome-wide methylation patterns using saliva- and whole blood-derived DNA from two …
… genome-wide methylation patterns using saliva- and whole blood-derived DNA from two …
DNA methylation-based age clocks: From age prediction to age reversion
… in this review including epigenetic age estimator (epigenetic age clock), epigenetic age (DNA
methylation age), phenotypic age, and epigenetic age acceleration are defined as follows. …
methylation age), phenotypic age, and epigenetic age acceleration are defined as follows. …
Identification and evaluation of age-correlated DNA methylation markers for forensic use
JL Park, JH Kim, E Seo, DH Bae, SY Kim… - Forensic Science …, 2016 - Elsevier
… (±6 years) with accuracy of 77.30% in the <60 years age group … our three DNA methylation
markers may be useful for age … universal DNA methylation markers that can be used for age …
markers may be useful for age … universal DNA methylation markers that can be used for age …
DNA methylation as a universal biomarker
VV Levenson - Expert review of molecular diagnostics, 2010 - Taylor & Francis
… of DNA methylation-based biomarkers. A number of excellent reviews have been published
recently on methylation and … Besides cancer, DNA methylation also appears to be useful for …
recently on methylation and … Besides cancer, DNA methylation also appears to be useful for …
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