Cinnamon extract reduces VEGF expression via suppressing HIF‐1α gene expression and inhibits tumor growth in mice

K Zhang, ES Han, TH Dellinger, J Lu… - Molecular …, 2017 - Wiley Online Library
… mediating reduced VEGF expression by CE, we examined the effects of CE on the expression
of HIF-1α, a major regulator of VEGF expression. HIF-1α is often over-expressed in many …

Novel angiogenesis inhibitory activity in cinnamon extract blocks VEGFR2 kinase and downstream signaling

J Lu, K Zhang, S Nam, RA Anderson, R Jove… - …, 2010 - academic.oup.com
… Our data revealed a novel activity in cinnamon and identified a natural VEGF inhibitor that
… in vitro , melanoma tumor growth in mice and VEGF expression in melanoma ( 45 , 46 ). In …

Cinnamon extract inhibits angiogenesis in zebrafish and human endothelial cells by suppressing VEGFR 1, VEGFR 2, and PKC‐mediated MAP kinase

RR Bansode, TC Leung, P Randolph… - Food science & …, 2013 - Wiley Online Library
… Inhibitory effects of cinnamon extract on TPA-induced PKC expression in HUVEC … inhibition
of the expression of the VEGF receptors in the presence of cinnamon extract, we investigated …

Water extract of Cinnamomum cassia suppresses angiogenesis through inhibition of VEGF receptor 2 phosphorylation

EC Kim, HJ Kim, TJ Kim - Bioscience, Biotechnology, and …, 2015 - academic.oup.com
… Therefore, we further performed a zymogram assay to examine the effect of CCWE on the
VEGF-stimulated expression of MMP-2 and MMP-9. Gelatin zymography revealed that the …

Cinnamon polyphenol extract regulates tristetraprolin and related gene expression in mouse adipocytes

H Cao, RA Anderson - Journal of Agricultural and food chemistry, 2011 - ACS Publications
… This study demonstrated that CPE rapidly induces TTP mRNA and reduces VEGF mRNA
and affects the expression of a number of other genes in the cultured adipocytes. …

Cinnamon extract suppresses tumor progression by modulating angiogenesis and the effector function of CD8+ T cells

HK Kwon, WK Jeon, JS Hwang, CG Lee, JS So… - Cancer letters, 2009 - Elsevier
… of cinnamon based on the finding that cinnamon extract reduced the levels of pro-angiogenic
factors (EGF, VEGF… cell lines with cinnamon extract abrogated the expression of Cox-2 and …

[PDF][PDF] Antiangiogenic activities of cinnamon, black and green tea extracts on experimentally induced breast cancer in rats

HR Madkor, SW Mansour, MA Khalil - Asian J Biochem, 2012 - researchgate.net
… showed that Cinnamon extract decrease serum levels of proangiogenic factors VEGF, bFGF,
… and vascularization by inhibiting of the expression of pro-angiogenic growth factors in vitro …

Effects of Cinnamon on VEGF and NF-κB Immunoreaction in The Lung Tissue of Rats with Experimentally Induced Diabetes

T Ertuğrul, G Sevilgen - Phoenix Medical Journal, 2022 - dergipark.org.tr
… investigate the effect of cinnamon on the immunohistochemical expression of VEGF and NF-…
The cinnamon group (n=8) received cinnamon extract by oral gavage at a dose of 0.5 mg/kg …

Cinnamon extract inhibits angiogenesis in zebrafish and human endothelial cells by suppressing VEGF and PKC‐mediated MAP kinase

RR Bansode, P Randolph, M Ahmedna - 2012 - Wiley Online Library
… Results show that cinnamon extract inhibited TPA-… Gene expression results in HUVEC
showed that cinnamon extract treatment inhibited TPA induction of PKC alpha mRNA expression

[PDF][PDF] Cinnamon pretreatment modulates gene expression of tight junction proteins in a rat model of stroke

S Najjary, H Mostafavi, H Feizi, F Moradi… - Avicenna Journal of …, 2024 - researchgate.net
… hydroalcoholic extract of cinnamon was probably involved in the reduction of VEGF gene
expression through … Cinnamon extract reduces VEGF expression via suppressing HIF‐1α gene …