Vascular endothelial growth factor (VEGF) signaling in tumor progression
R Roskoski Jr - Critical reviews in oncology/hematology, 2007 - Elsevier
… The VEGF/VEGFR (vascular endothelial growth factor/VEGF receptor) family is the most
studied … In the context of this review, tumor progression represents the process of tumor growth …
studied … In the context of this review, tumor progression represents the process of tumor growth …
Vascular endothelial growth factor (VEGF) mRNA expression in human tumor models of different histologies
DP Berger, L Herbstritt, WA Dengler, D Marme… - Annals of oncology, 1995 - Elsevier
… We studied the expression of VEGF mRNA in a panel of 65 different human tumor xeno-grafts
of various histologies using Northern and slot blot analyses. Analysis of vessel density was …
of various histologies using Northern and slot blot analyses. Analysis of vessel density was …
VEGF as a therapeutic target in cancer
N Ferrara - Oncology, 2005 - karger.com
… However, VEGF has other roles that influence tumor growth and progression, including
inhibiting functional maturation of dendritic cells [17] and enhanced adhesion of natural killer …
inhibiting functional maturation of dendritic cells [17] and enhanced adhesion of natural killer …
Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis
DJ Hicklin, LM Ellis - Journal of clinical oncology, 2005 - ascopubs.org
… angiogenesis by upregulating VEGF expression in breast, endometrial, pancreatic, and
colorectal cancers. Hepatocyte growth factor can induce VEGF expression in normal and …
colorectal cancers. Hepatocyte growth factor can induce VEGF expression in normal and …
[HTML][HTML] Pancreas microenvironment promotes VEGF expression and tumor growth: novel window models for pancreatic tumor angiogenesis and microcirculation
Y Tsuzuki, CM Carreira, M Bockhorn, L Xu… - Laboratory …, 2001 - Elsevier
… microenvironment enhances VEGF expression, which stimulates growth of PANC-1 … that
VEGF protein levels increased with tumor growth in both orthotopic and ectopic PANC-1 tumors. …
VEGF protein levels increased with tumor growth in both orthotopic and ectopic PANC-1 tumors. …
[HTML][HTML] VEGF expression in pancreatic cancer and other malignancies: a review of the literature
MI Costache, M Ioana, S Iordache, D Ene… - Romanian journal of …, 2015 - sciendo.com
… Thus, we find a high level of VEGF expression in the diseases … in angiogenesis where the
expression of VEGF is low: ischemic … VEGF-C may promote local tumor growth via paracrine …
expression of VEGF is low: ischemic … VEGF-C may promote local tumor growth via paracrine …
Effects of anti-VEGF treatment duration on tumor growth, tumor regrowth, and treatment efficacy
A Bagri, L Berry, B Gunter, M Singh, I Kasman… - Clinical Cancer …, 2010 - AACR
… -VEGF sensitivity was not a function of tumor growth rate (Supplementary Fig. S1). We also
evaluated if VEGF dependence was a function of VEGF expression … tumor VEGF expression …
evaluated if VEGF dependence was a function of VEGF expression … tumor VEGF expression …
VEGF–integrin interplay controls tumor growth and vascularization
S De, O Razorenova, NP McCabe… - Proceedings of the …, 2005 - National Acad Sciences
… tumor αvβ3 is also able to promote VEGF expression. Using … expression, we noted a 6-fold
difference in VEGF expression … line that lacks β3 expression and that VEGF expression by the …
difference in VEGF expression … line that lacks β3 expression and that VEGF expression by the …
Vascular endothelial growth factor (VEGF) expression and survival in human epithelial ovarian carcinomas
EM Hartenbach, TA Olson, JJ Goswitz, D Mohanraj… - Cancer letters, 1997 - Elsevier
… tumor specimens for VEGF expression and its relationship to survival outcomes in patients
diagnosed with advanced stage (III/IV) ovarian carcinoma. In addition, tumor … tumor growth …
diagnosed with advanced stage (III/IV) ovarian carcinoma. In addition, tumor … tumor growth …
Downregulation of VEGF-C expression in lung and colon cancer cells decelerates tumor growth and inhibits metastasis via multiple mechanisms
… Taken together, our results demonstrate that downregulation of VEGF-C in cancer cells
expressing its receptor VEGFR3 inhibits tumor growth and metastasis via multiple effects …
expressing its receptor VEGFR3 inhibits tumor growth and metastasis via multiple effects …
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