… To overcome current limitations, we developed methylSig, a genome-wide DNA methylation
analysis pipeline for use with bis-seq, RRBS or ERRBS data. MethylSig utilizes a beta-…

… There are numerous approaches to decipher a whole genome DNA methylation profile (“…
methods, whole genome bisulfite-sequencing (BS-seq), involves treatment of DNA with sodium …

… of DNA methylation as an inhibitor of gene expression is still pervasive. Global and unbiased
DNA methylation analysis protocols such as whole genome … role of DNA methylation, with …

… In addition to genetic factors, epigenetic mechanisms, primarily DNA methylation, which … In
this study, we have performed the first whole-genome DNA methylation profiling of peripheral …

… This study aimed to screen DNA methylation characteristics in sperm that correlate with bull
fertility. The identified DNA methylation patterns could be used to improve our decisive ability …

… need to encompass the whole genome. Moreover, given the … -seq, a whole genome
sequencing technique incorporating an … the methylated fraction of a genome (the “methylome”). …

… by investigating the DNA methylation levels of genes in peripheral blood mononuclear cells
on a genome-wide scale. We hypothesized that the DNA methylation profiles of peripheral …

… DNA methylation analysis, with a particular emphasis on genome-scale DNA methylation
analysis … challenges that are unique to DNA methylation analysis are outlined. Although some …

… DNA methylation analysis consists of five steps following DNA extraction from either fresh of
… : Bisulfite conversion ; DNA restoration (for FFPE specimens); whole genome amplification; …

… too low to precisely pinpoint the methylated CpG sites in the genome [Citation11,Citation12]…
whole genome DNA methylation profiling data from wild guinea pig using methylated DNA-…