… of aging-related diseases, such as lung cancer. Using data on 2,029 females from the
Women's Health Initiative, we examined whether baseline measures of “intrinsic epigenetic age …

… aging as assessed by 2 DNA methylation-based … health outcomes (eg, CVD) in the Women’s
Health Initiative (WHI) (8), we also examine the timing of VMS in relation to epigenetic aging…

… burden at an advanced age. Epigenetic age is a composite measure of DNA methylation (DNAm) …
with chronologic and phenotypic age. These DNAm signatures are associated with …

… of aging known as the “epigenetic clock.” However, it is unknown whether breast tissue samples
from healthy women show a similar accelerated aging … DNA methylation (DNAm) age in …

… Women's Health Initiative (WHI), a prospective cohort of 161,808 postmenopausal women
from across the United States, recruited from 1993 to 1998, who were between the ages of 50 …

… diet quality scores based on self-reported food frequency questionnaire data and five
measures of epigenetic aging based on DNA methylation (DNAm) data from peripheral blood. …

… participants in a subset of the original Women’s Health Initiative (WHI) participants and a …
immunosenescence and healthy aging, as it is a sample of women ranging in age from 50 …

… In the multivariate-adjusted analyses, we controlled for age and BMI along with plasma
creatinine, ethnicity (white/not white) and MTHFR C677T genotype as these three variables were …

… aging, including composite DNA methylation (DNAm) markers that predict … the Women's
Health Initiative (WHI), a large racially and ethnically diverse cohort of postmenopausal women …

… women, estradiol (E2) and sex hormone-binding globulin were assayed in baseline serum
samples. For WHI participants with DNA methylation … age at menopause, race/ethnicity, age at …