Zebrafish embryos as a screen for DNA methylation modifications after compound exposure

MC Bouwmeester, S Ruiter, T Lommelaars… - Toxicology and applied …, 2016 - Elsevier
… In this study, we examined the applicability of the zebrafish embryo as a screening model
for DNA methylation modifications. Embryos were exposed from 0 to 72 h post fertilization (hpf) …

Zebrafish as a model to study the role of DNA methylation in environmental toxicology

JH Kamstra, P Aleström, JM Kooter, J Legler - Environmental Science and …, 2015 - Springer
… in DNA methylation during … DNA methylation (eg, methyl transferases, demethylation
mechanisms, methylcytosine-binding proteins). Since DNA methylation patterns during embryonic

Developmental features of DNA methylation during activation of the embryonic zebrafish genome

IS Andersen, AH Reiner, H Aanes, P Aleström, P Collas - Genome biology, 2012 - Springer
… pre-MBT period in zebrafish, we address here whether DNA methylation may pre-pattern
early … in promoter DNA methylation before, at the time of, and after ZGA in the context of DNA

Global and gene specific DNA methylation changes during zebrafish development

X Fang, J Corrales, C Thornton, BE Scheffler… - … and Physiology Part B …, 2013 - Elsevier
DNA methylation is dynamic … on DNA methylation changes during very early embryogenesis.
In this study, global and gene specific DNA methylation in zebrafish (Danio rerio) embryos, …

DNA methylation profiling in zebrafish

SF Wu, H Zhang, SS Hammoud, M Potok, DA Nix… - Methods in cell …, 2011 - Elsevier
… To extract genomic DNA from zebrafish adult tissue, embryos, or cell lines, we utilize the
Gentra Puregene Tissue Kit (Qiagen Inc., Valencia, CA) with the following modifications. Instead …

Modulation of plasmid DNA methylation and expression in zebrafish embryos

P Collas - Nucleic acids research, 1998 - academic.oup.com
… Gene expression is under the influence of DNA methylation … expression in zebrafish embryos
by altering DNA methylation with … into zebrafish eggs becomes gradually methylated during …

DNA methylation in zebrafish

MG Goll, ME Halpern - Progress in molecular biology and translational …, 2011 - Elsevier
… that zebrafish might have an efficient DNA methylation system … in zebrafish relied on injection
of naked, linearized DNA into … The amount of non-CpG methylation in the zebrafish embryo

Absence of genome-wide changes in DNA methylation during development of the zebrafish

D Macleod, VH Clark, A Bird - Nature genetics, 1999 - nature.com
… highly methylated at testable sites in sperm, adult and embryonic stages of the zebrafish. …
The genome as a whole is highly methylated at HpaII sites in the developing embryo, sperm …

DNA methylation and gene expression alterations in zebrafish embryos exposed to cadmium

X Bian, Y Gao - Environmental Science and Pollution Research, 2021 - Springer
… mechanism of DNA methylation in zebrafish embryo under … DNA methylation level of
zebrafish embryo, and we observed global methylation and signaling pathway-related gene DNA

Effects on specific promoter DNA methylation in zebrafish embryos and larvae following benzo [a] pyrene exposure

J Corrales, X Fang, C Thornton, W Mei… - … and Physiology Part C …, 2014 - Elsevier
… human disease in genome-wide association studies have zebrafish orthologs. … DNA
methylation in zebrafish whole embryos and larvae following a parental and continued embryonic