Abiraterone, Olaparib, or Abiraterone+ Olaparib in First-line Metastatic Castration-Resistant Prostate Cancer with DNA Repair Defects (BRCAAway)

M Hussain, M Kocherginsky, N Agarwal… - Clinical Cancer …, 2024 - aacrjournals.org
Purpose: Deleterious germline/somatic homologous recombination repair mutations
(HRRm) are present in∼ 25% of patients with metastatic castration-resistant prostate cancer …
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Abiraterone, Olaparib, or Abiraterone+ Olaparib in First-line Metastatic Castration-Resistant Prostate Cancer with DNA Repair Defects (BRCAAway)

M Hussain, M Kocherginsky, N Agarwal… - … cancer research: an … - pubmed.ncbi.nlm.nih.gov
Purpose Deleterious germline/somatic homologous recombination-repair mutations (HRRm)
are present in~ 25% of metastatic castration resistant prostate cancer (mCRPC) patients …