[HTML][HTML] Enhanced CRISPR-based DNA demethylation by Casilio-ME-mediated RNA-guided coupling of methylcytosine oxidation and DNA repair pathways

A Taghbalout, M Du, N Jillette, W Rosikiewicz… - Nature …, 2019 - nature.com
Here we develop a methylation editing toolbox, Casilio-ME, that enables not only RNA-
guided methylcytosine editing by targeting TET1 to genomic sites, but also by co-delivering …

Enhanced CRISPR-based DNA demethylation by Casilio-ME-mediated RNA-guided coupling of methylcytosine oxidation and DNA repair pathways.

A Taghbalout, M Du, N Jillette… - Nature …, 2019 - search.ebscohost.com
Here we develop a methylation editing toolbox, Casilio-ME, that enables not only RNA-
guided methylcytosine editing by targeting TET1 to genomic sites, but also by co-delivering …

Enhanced CRISPR-based DNA demethylation by Casilio-ME-mediated RNA-guided coupling of methylcytosine oxidation and DNA repair pathways.

A Taghbalout, M Du, NL Jillette, W Rosikiewicz, A Rath… - 2019 - mouseion.jax.org
Here we develop a methylation editing toolbox, Casilio-ME, that enables not only RNA-
guided methylcytosine editing by targeting TET1 to genomic sites, but also by co-delivering …

Enhanced CRISPR-based DNA demethylation by Casilio-ME-mediated RNA-guided coupling of methylcytosine oxidation and DNA repair pathways

A Taghbalout, M Du, N Jillette, W Rosikiewicz… - Nature …, 2019 - ideas.repec.org
Here we develop a methylation editing toolbox, Casilio-ME, that enables not only RNA-
guided methylcytosine editing by targeting TET1 to genomic sites, but also by co-delivering …

[PDF][PDF] Enhanced CRISPR-based DNA demethylation by Casilio-ME-mediated RNA-guided coupling of methylcytosine oxidation and DNA repair pathways.

A Taghbalout, M Du, NL Jillette, W Rosikiewicz, A Rath - core.ac.uk
Casilio-ME1 is a three-component DNA Methylation Editing platform built on Casilio which
uses nuclease-deficient Cas9 (dCas9), an effector module made of Pumilio/FBF (PUF) …

[HTML][HTML] Enhanced CRISPR-based DNA demethylation by Casilio-ME-mediated RNA-guided coupling of methylcytosine oxidation and DNA repair pathways

A Taghbalout, M Du, N Jillette… - Nature …, 2019 - ncbi.nlm.nih.gov
Here we develop a methylation editing toolbox, Casilio-ME, that enables not only RNA-
guided methylcytosine editing by targeting TET1 to genomic sites, but also by co-delivering …

Enhanced CRISPR-based DNA demethylation by Casilio-ME-mediated RNA-guided coupling of methylcytosine oxidation and DNA repair pathways

A Taghbalout, M Du, N Jillette… - Nature …, 2019 - ui.adsabs.harvard.edu
Here we develop a methylation editing toolbox, Casilio-ME, that enables not only RNA-
guided methylcytosine editing by targeting TET1 to genomic sites, but also by co-delivering …

Enhanced CRISPR-based DNA demethylation by Casilio-ME-mediated RNA-guided coupling of methylcytosine oxidation and DNA repair pathways.

A Taghbalout, M Du, N Jillette, W Rosikiewicz… - Nature …, 2019 - europepmc.org
Here we develop a methylation editing toolbox, Casilio-ME, that enables not only RNA-
guided methylcytosine editing by targeting TET1 to genomic sites, but also by co-delivering …

Enhanced CRISPR-based DNA demethylation by Casilio-ME-mediated RNA-guided coupling of methylcytosine oxidation and DNA repair pathways

A Taghbalout, M Du, N Jillette… - Nature …, 2019 - pubmed.ncbi.nlm.nih.gov
Here we develop a methylation editing toolbox, Casilio-ME, that enables not only RNA-
guided methylcytosine editing by targeting TET1 to genomic sites, but also by co-delivering …

Enhanced CRISPR-based DNA demethylation by Casilio-ME-mediated RNA-guided coupling of methylcytosine oxidation and DNA repair pathways

A Taghbalout, M Du, N Jillette, W Rosikiewicz… - Nature …, 2019 - cir.nii.ac.jp
抄録< jats: title> Abstract</jats: title>< jats: p> Here we develop a methylation editing
toolbox,< jats: italic> Casilio-ME</jats: italic>, that enables not only RNA-guided …