Behavior of homing endonuclease gene drives targeting genes required for viability or female fertility with multiplexed guide RNAs

G Oberhofer, T Ivy, BA Hay - Proceedings of the National …, 2018 - National Acad Sciences
A gene drive method of particular interest for population suppression utilizes homing
endonuclease genes (HEGs), wherein a site-specific, nuclease-encoding cassette is copied …

Behavior of homing endonuclease gene drives targeting genes required for viability or female fertility with multiplexed guide RNAs.

G Oberhofer, T Ivy, BA Hay - … of the National Academy of Sciences of …, 2018 - europepmc.org
Results HEG Design. We selected two recessive target genes for our HEG constructs, yellow-
g (yg) and deformed (Dfd). The ortholog of yellow-g has been used previously as a target …

Behavior of homing endonuclease gene drives targeting genes required for viability or female fertility with multiplexed guide RNAs

G Oberhofer, T Ivy, BA Hay - Proceedings of the National …, 2018 - pubmed.ncbi.nlm.nih.gov
A gene drive method of particular interest for population suppression utilizes homing
endonuclease genes (HEGs), wherein a site-specific, nuclease-encoding cassette is copied …

[PDF][PDF] Behavior of homing endonuclease gene drives targeting genes required for viability or female fertility with multiplexed guide RNAs

G Oberhofera, T Ivya, BA Haya - PNAS - core.ac.uk
Results HEG Design. We selected two recessive target genes for our HEG constructs, yellow-
g (yg) and deformed (Dfd). The ortholog of yellow-g has been used previously as a target …

[PDF][PDF] Behavior of homing endonuclease gene drives targeting genes required for viability or female fertility with multiplexed guide RNAs

G Oberhofera, T Ivya, BA Haya - PNAS - researchgate.net
Results HEG Design. We selected two recessive target genes for our HEG constructs, yellow-
g (yg) and deformed (Dfd). The ortholog of yellow-g has been used previously as a target …

[PDF][PDF] Behavior of homing endonuclease gene drives targeting genes required for viability or female fertility with multiplexed guide RNAs

G Oberhofera, T Ivya, BA Haya - PNAS - authors.library.caltech.edu
Results HEG Design. We selected two recessive target genes for our HEG constructs, yellow-
g (yg) and deformed (Dfd). The ortholog of yellow-g has been used previously as a target …

[PDF][PDF] Behavior of homing endonuclease gene drives targeting genes required for viability or female fertility with multiplexed guide RNAs

G Oberhofera, T Ivya, BA Haya - PNAS - haylab.caltech.edu
Results HEG Design. We selected two recessive target genes for our HEG constructs, yellow-
g (yg) and deformed (Dfd). The ortholog of yellow-g has been used previously as a target …

[PDF][PDF] Behavior of homing endonuclease gene drives targeting genes required for viability or female fertility with multiplexed guide RNAs

G Oberhofer, T Ivy, BA Hay - scholar.archive.org
A gene drive method of particular interest for population suppression utilizes homing
endonuclease genes (HEGs), wherein a site-specific nuclease-encoding cassette is copied …

Behavior of homing endonuclease gene drives targeting genes required for viability or female fertility with multiplexed guide RNAs

G Oberhofer, T Ivy, BA Hay - Proceedings of the National Academy of …, 2018 - JSTOR
A gene drive method of particular interest for population suppression utilizes homing
endonuclease genes (HEGs), wherein a site-specific, nuclease-encoding cassette is copied …

Behavior of homing endonuclease gene drives targeting genes required for viability or female fertility with multiplexed guide RNAs

G Oberhofer, T Ivy, BA Hay - bioRxiv, 2018 - biorxiv.org
A gene drive method of particular interest for population suppression utilizes homing
endonuclease genes (HEGs), wherein a site-specific nuclease-encoding cassette is copied …