Epstein-Barr virus is present in the brain of most cases of multiple sclerosis and may engage more than just B cells
… To determine if there was any correlation between EBV positivity in the brain and immune
infiltration, tissue sections were stained with haematoxylin and eosin (H&E) and assessed for …
infiltration, tissue sections were stained with haematoxylin and eosin (H&E) and assessed for …
[PDF][PDF] Methylprednisolone treatment, immune activation, and intrathecal inflammation in multiple sclerosis
F Sellebjerg - Danish Med Bull, 2004 - Citeseer
… In contrast, in RRMS disease activity correlated with the … activity in CSF correlated with the
area of enhancement on T1-weighted MRI, and in two other studies increased MMP-9 activity …
area of enhancement on T1-weighted MRI, and in two other studies increased MMP-9 activity …
Anti-Epstein–Barr virus antibodies as serological markers of multiple sclerosis: a prospective study among United States military personnel
KL Munger, LI Levin, EJ O'Reilly… - Multiple Sclerosis …, 2011 - journals.sagepub.com
… this study was the humoral immune response to the virus in … levels were weakly inversely
correlated with EBNA complex IgG … (OH)D may influence the immune response to EBV, we also …
correlated with EBNA complex IgG … (OH)D may influence the immune response to EBV, we also …
An appraisal of antigen identification and IgG effector functions driving host immune responses in multiple sclerosis
X Yu, Z Zizzo, PGE Kennedy - Multiple Sclerosis and Related Disorders, 2021 - Elsevier
… (OCB) are the most characteristic features of multiple sclerosis (MS), a neuroinflammatory …
reduced clinical and magnetic resonance imaging (MRI) evidence of disease activity, although …
reduced clinical and magnetic resonance imaging (MRI) evidence of disease activity, although …
A case of double standard: Sex differences in multiple sclerosis risk factors
B Angeloni, R Bigi, G Bellucci, R Mechelli… - International Journal of …, 2021 - mdpi.com
… sharper inflammatory pattern at magnetic resonance imaging (MRI) [11], … The aim of this
review is to analyze the possible correlation … between higher humoral antivirus response and the …
review is to analyze the possible correlation … between higher humoral antivirus response and the …
[HTML][HTML] The CD8 T cell-Epstein-Barr virus-B cell trialogue: a central issue in multiple sclerosis pathogenesis
C Veroni, F Aloisi - Frontiers in immunology, 2021 - frontiersin.org
… immune system due to its ability to establish a life-long latent infection in B cells, reactivate
periodically and induce a very effective immune response … damage positively correlates with …
periodically and induce a very effective immune response … damage positively correlates with …
[引用][C] Heterogeneity in multiple sclerosis. Insights from imaging, immunology and genetics
I Smets - 2018
MINI-review of Epstein-Barr virus involvement in multiple sclerosis etiology and pathogenesis
F Aloisi, AH Cross - Journal of Neuroimmunology, 2022 - Elsevier
… as other factors influencing immune system function, including transient immunosuppression
due to stressful events or co-infections, could alter the immune response to EBV to favour …
due to stressful events or co-infections, could alter the immune response to EBV to favour …
Expanded T lymphocytes in the cerebrospinal fluid of multiple sclerosis patients are specific for Epstein-Barr-virus-infected B cells
A Gottlieb, HPT Pham, JG Saltarrelli… - Proceedings of the …, 2024 - National Acad Sciences
… initial infection with EBV (5, 6), and correlation of various markers of EBV activity with MS
disease … This is additional strong evidence for a role of the anti-EBV immune response in MS, …
disease … This is additional strong evidence for a role of the anti-EBV immune response in MS, …
EBV and MS: Major cause, minor contribution or red-herring?
S Burnard, J Lechner-Scott, RJ Scott - Multiple sclerosis and related …, 2017 - Elsevier
… MS development, and an overall altered immune response to EBV found in peripheral blood
… ) in response to LCL preceding MRI activity has been reported, with a correlation shown as …
… ) in response to LCL preceding MRI activity has been reported, with a correlation shown as …