… While in this study we focused on the autocrine role of IL-8, a paracrine role should not be
overlooked as many types of cells produce IL-8 after infection with B. henselae (Fig. 1A and B)…

… IL-8 may have an autocrine role in disease progression … of a leading role for VEGF in
Bartonella henselae-induced en… Interleukin-8 as a macrophage-derived mediator of angiogenesis. …

… of Bartonella henselae infection for cats as compared to humans and strongly suggest that
an autocrine … henselae-mediated angiogenesis induction implies autocrine VEGF production …

… Thus MCP1 could play dual roles in B. henselae-induced angiogenesis by acting in an
autocrine manner on endothelial cells to promote angiogenesis, while recruiting macrophages, …

… propose that infected MSCs may support this angiogenic loop. A role for MSCs can be envisioned
in … henselae-induced angiogenesis may allow the development of targeted therapeutic …

… infected macrophage effector cell secretes VEGF and interleukin-8 (IL8), which … roles in the
potential paracrine loop model of B. henselaeinduced angiogenesis by acting in an autocrine…

… genes encoding angioproliferative factors such as VEGF, interleukin-8 (IL-8), adrenomedullin
… Interleukin-8 (IL-8), a potent promoter of angiogenesis, has been observed to be enhanced …

… henselae-induced angiogenesis. BA is a manifestation of … of angiogenesis have been
described, including interleukin-8 (… , or angiogenic cytokines and growth factors with autocrine or …

… of the chemokine CXCL8, which has been shown to act in an autocrine manner in B. …
Autocrine role for interleukin-8 in Bartonella henselae-induced angiogenesis. Infect Immun 74, 5185…

… induce pathological angiogenesis in the mammalian host. Bartonella-induced angiogenesis
leads … henselae induced production of VEGF from HBVPs in a dose-dependent manner with …