… suitable vehicles for delivery into the CNS through systemic … of the physiology of the CNS
offer a plethora of opportunities for … proteins offers drug delivery tools for specific CNS diseases …

… suitable vehicles for delivery into the CNS through systemic … of the physiology of the CNS
offer a plethora of opportunities for … proteins offer drug delivery tools for specific CNS diseases …

… BBB-targeting, protein-based nanomedicines for drug and nucleic acid delivery to the CNS.
… nanocomplexes for the delivery of therapeutic nucleic acids to the brain. Biomaterials 2013; …

… , and RVG peptide as BBB targeting ligand, has been designed … successfully develop
nanomedicine for nucleic acid delivery, … Thus, with the better understanding of nanomedicine in …

… US Food and Drug Administration as the first nanomedicine for … nucleic acid and its
susceptibility to enzymatic hydrolysis in vivo may pose a problem in the delivery of nucleic acid drugs…

… and receptors have been used for BBB targeting among them are transferrin receptor 1 (TfR1), …
small molecules, proteins or nucleic acid-based therapeutics into the CNS [Citation79]. A …

… small molecular drugs and protein-based therapeutics … of dendrimers to increase BBB targeting
and penetrating. One … bioactive molecules, such as nucleic acids, enzymes, and proteins. …

… a stabilizer) and decorated with the BBB targeting peptide Tg (… stability and brain accumulation
of these nucleic acid-based … the delivery of protein-based NPs, and components of amino …

… brain. This review comprehensively depicts challenges to the brain targeted drug delivery,
mechanisms of drug … of endogenous cells as NPs delivery cells and novel targeting ligands …

… in siRNA brain delivery in … delivery of siRNA-based therapy for brain diseases, highlight
recent advances in the development and engineering of siRNA nanomedicines for various brain …