Androgen receptor variant-driven prostate cancer: clinical implications and therapeutic targeting

ES Antonarakis, AJ Armstrong, SM Dehm… - Prostate cancer and …, 2016 - nature.com
… exon of AR-V7) splice acceptor. Further, knockdown of these factors impaired splicing of
exon 3 to CE3 but not exons 3 to 4 in LNCaP95, a cell line derived from the parental LNCaP line …

BCL2 Family of Apoptosis-Related Genes: Functions and Clinical Implications in Cancer

H Thomadaki, A Scorilas - Critical reviews in clinical laboratory …, 2006 - Taylor & Francis
cell receptor triggering in human T cells, implicating BIM as a mediator of death receptor-independent
activation-induced cellacceptor protein might be implicated in murine T cell

Platelet activating factor (paf) A review of its effects, antagonists and possible future clinical implications (part I)

M Koltai, D Hosford, P Guinot, A Esanu, P Braquet - Drugs, 1991 - Springer
… the presence of PAF receptors in cell membranes. Therefore, a … Although the number of
natural and synthetic PAF receptor … These findings suggest that this high affinity acceptor site may …

Glycoproteins: their structure, biosynthesis and possible clinical implications

H Schachter - Clinical biochemistry, 1984 - Elsevier
… reticulum to the cell surface, and in recognition phenomena such as receptormediated
endocytosis, … The cell surface carbohydrate of some transformed cell lines tends to be more highly …

Carbon monoxide: mechanisms of action and potential clinical implications

L Rochette, Y Cottin, M Zeller, C Vergely - Pharmacology & therapeutics, 2013 - Elsevier
cell proliferation associated with increasing cellular antioxidant activities. Re-endothelialization
of a denuded arterial surface is achieved by the migration and proliferation of cells from …

Cell of origin of glioma: biological and clinical implications

SR Alcantara Llaguno, LF Parada - British journal of cancer, 2016 - nature.com
… repeat with splice acceptor) system that employs Rous sarcoma virus-based vectors that
are then injected into mice expressing the TVA receptor under the control of cell type-specific …

Clinical implications of genetic defects in G proteins: the molecular basis of McCune-Albright syndrome and Albright hereditary osteodystrophy

MD Ringel, WF Schwindinger, MA Levine - Medicine, 1996 - journals.lww.com
… Because each affected cell type expresses different receptors, a postreceptor defect in a
protein that is present in all affected tissues was proposed as a unifying molecular etiology for …

Glycosylation and Its Role in Immune Checkpoint Proteins: From Molecular Mechanisms to Clinical Implications

J Liu, X Xu, H Zhong, M Yu, N Abuduaini, S Zhang… - Biomedicines, 2024 - mdpi.com
cell death-ligand 1 (PD-L1) blocks T-cell activation and cytokine production once it binds to
programmed cell … /T-cell receptor (TCR) signaling by engaging with PD-L1, which leads to T-…

Reverse cholesterol transport—a review of the process and its clinical implications

SA Hill, MJ McQueen - Clinical biochemistry, 1997 - Elsevier
… (2) Pre-β 1 HDL binds to the cell surface via specific receptors and cholesterol is transferred
to the … These newly generated pre-β HDL particles act as acceptors for cellular cholesterol …

Prostasomes are mediators of intercellular communication: from basic research to clinical implications

G Ronquist - Journal of internal medicine, 2012 - Wiley Online Library
… bioactive molecules (eg receptors and enzymes) that promote … from one cell (the immobile
prostate acinar cell) to another (… main categories depending on the acceptor amino acid of the …