A novel human-specific soluble vascular endothelial growth factor receptor 1: cell type-specific splicing and implications to vascular endothelial growth factor …
S Sela, A Itin, S Natanson-Yaron, C Greenfield… - Circulation …, 2008 - Am Heart Assoc
… intron 14 splice acceptor site, only takes … receptor or 1 of the 2 truncated soluble receptors,
are mutually exclusive. Thus, the highly preferred utilization of the intron 14 splice acceptor in …
are mutually exclusive. Thus, the highly preferred utilization of the intron 14 splice acceptor in …
Teaching old receptors new tricks: biasing seven-transmembrane receptors
… be due to cell-specific effects and receptor heterogeneity 47 . … In this section, we highlight
the physiological consequences … and an acceptor probe can be attached to the receptor and β-…
the physiological consequences … and an acceptor probe can be attached to the receptor and β-…
Mechanisms of neuronal cell death in ischemic stroke and their therapeutic implications
… Alternatively, cell surface receptors can be activated by specific ligands that bind to “death
receptors.” AIF, apoptosis-inducing factor; Cytc, cytochrome C [Color figure can be viewed at …
receptors.” AIF, apoptosis-inducing factor; Cytc, cytochrome C [Color figure can be viewed at …
The molecular mechanisms underlying the regulation of the biological activity of corticotropin-releasing hormone receptors: implications for physiology and …
EW Hillhouse, DK Grammatopoulos - Endocrine reviews, 2006 - academic.oup.com
… mechanisms via paracrine or autocrine activation of specific receptors expressed on the cell
membrane of target cells. These CRH receptors (CRH-Rs) and the mechanisms regulating …
membrane of target cells. These CRH receptors (CRH-Rs) and the mechanisms regulating …
Intracellular redox status and oxidative stress: implications for cell proliferation, apoptosis, and carcinogenesis
… agents including electron acceptors, electron donors, and hydride acceptors can be … receptor
superfamily called the death receptors (TNFR1, FAS, and TRAIL). Receptor-mediated cell …
superfamily called the death receptors (TNFR1, FAS, and TRAIL). Receptor-mediated cell …
Nanomaterials for cancer precision medicine
Y Wang, S Sun, Z Zhang, D Shi - Advanced materials, 2018 - Wiley Online Library
… emerged with specific clinical implications and challenges that … to treat diseases in tissues
with HA receptors, such as liver and … tumor cell uptake has also been found with PGA receptor-…
with HA receptors, such as liver and … tumor cell uptake has also been found with PGA receptor-…
[HTML][HTML] In vivo genome editing in animals using AAV-CRISPR system: applications to translational research of human disease
… In addition, we discuss the clinical implications and potential strategies to overcome off-… to
disrupt both of the endogenous T-cell receptor ( TCR) and beta-2 microglobulin ( B2M) genes. …
disrupt both of the endogenous T-cell receptor ( TCR) and beta-2 microglobulin ( B2M) genes. …
Transport of cholesterol across a BeWo cell monolayer: implications for net transport of sterol from maternal to fetal circulation
KE Schmid, WS Davidson, L Myatt, LA Woollett - Journal of lipid research, 2003 - ASBMB
… cellular cholesterol concentration further increased the amount of cholesterol transported to
the basolateral acceptors… into the cells and effluxed to acceptors in the basolateral chamber. …
the basolateral acceptors… into the cells and effluxed to acceptors in the basolateral chamber. …
Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis
MS Brown, JL Goldstein - Annual review of biochemistry, 1983 - annualreviews.org
… to a cell surface receptor. Although macrophages express few receptors for normal plasma …
or excreted from the cell, depending on whether or not a cholesterol acceptor is present in the …
or excreted from the cell, depending on whether or not a cholesterol acceptor is present in the …
… activation of drugs by cytochrome P450 enzymes: Biochemical insights into mechanism-based inactivation by fibroblast growth factor receptor inhibitors and chemical …
LWT Tang, ECY Chan - Biochemical Pharmacology, 2022 - Elsevier
… which bears profound clinical implications (ie… cellular macromolecules, the likelihood of this
occurring in reality is mitigated by the low intrinsic chemical reactivity of the Michael acceptor …
occurring in reality is mitigated by the low intrinsic chemical reactivity of the Michael acceptor …