Inherited disorders of human Toll‐like receptor signaling: immunological implications

CL Ku, K Yang, J Bustamante, A Puel… - Immunological …, 2005 - Wiley Online Library
… one of the two phospho-acceptor serine residues on IκBα, … age, suggesting that T-cell- and
B-cell-specific responses can … of the clinical features and an international clinical survey is …

Clinical implications of mitochondrial dysfunction

S Muravchick, RJ Levy, DC Warltier - The Journal of the American …, 2006 - pubs.asahq.org
… molecular oxygen, the final acceptor of electrons, to water at that site. … cell surface N -methyl-d-aspartate
(NMDA) receptors by neurotransmitters such as glutamate or by “death receptors

The evolution of protein kinase inhibitors from antagonists to agonists of cellular signaling

AC Dar, KM Shokat - Annual review of biochemistry, 2011 - annualreviews.org
… because the phospho-acceptor pocket and domains outside of … Shown is the insulin receptor
kinase in complex with ATP and … The clinical implications of these findings for patients with …

Interleukin‐7 receptor α (IL‐7Rα) deficiency: cellular and molecular bases. Analysis of clinical, immunological, and molecular features in 16 novel patients

S Giliani, L Mori, G De Saint Basile… - Immunological …, 2005 - Wiley Online Library
… compound for one splice-site mutation at the acceptor splice-site of intron 4 and for a …
functional consequences of mutations that do not interfere with the presence of IL-7Rα at the cell

Application of fluorescence resonance energy transfer in the clinical laboratory: routine and research

J Szöllosi, S Damjanovich… - Cytometry: The Journal of …, 1998 - Wiley Online Library
… As a consequence, the fluorescence intensity of the acceptor … oligomeric complex with
CD3/T cell receptor (TCR), CD45, … role of the CD7 molecule in T cell activation (59). Flow …

Carbon monoxide: mechanisms of action and potential clinical implications

L Rochette, Y Cottin, M Zeller, C Vergely - Pharmacology & therapeutics, 2013 - Elsevier
cell proliferation associated with increasing cellular antioxidant activities. Re-endothelialization
of a denuded arterial surface is achieved by the migration and proliferation of cells from …

Cellular cholesterol efflux pathways: impact on intracellular lipid trafficking and methodological considerations

I Zanotti, E Favari, F Bernini - Current pharmaceutical …, 2012 - ingentaconnect.com
… serum/plasma as cholesterol acceptor are large, for the clinical implications (see below) or
… The liver X receptor: Control of cellular lipid homeostasis and beyond Implications for drug …

Nuclear receptors PXR and CAR: implications for drug metabolism regulation, pharmacogenomics and beyond

X Chai, S Zeng, W Xie - Expert opinion on drug metabolism & …, 2013 - Taylor & Francis
… Binding of ligands to these receptors results in the recruitment of the co-activators, thereby
… nuclear receptors, pregnane X receptor (PXR) and constitutive androstane receptor (CAR). …

Apoptosis: a basic biological phenomenon with wide‐ranging implications in human disease

B Fadeel, S Orrenius - Journal of internal medicine, 2005 - Wiley Online Library
… and acceptor cell [50]. … receptors do not bind to PS directly, but rather via soluble ‘bridging’
proteins that bind to both the signal on the apoptotic cell and the receptor on the engulfing cell

Fcγ-receptor–mediated trogocytosis impacts mAb-based therapies: historical precedence and recent developments

RP Taylor, MA Lindorfer - Blood, The Journal of the American …, 2015 - ashpublications.org
cell by cell-surface receptors on the acceptor cell. Secondly, in an energy-requiring process
that includes actin polymerization, membrane remodeling, and signaling, portions of the …