Peptidomimetics for receptor ligands—discovery, development, and medical perspectives
A Giannis, T Kolter - Angewandte Chemie International Edition …, 1993 - Wiley Online Library
… neuromodulators, and hormones influence cell-cell commu… The same pharmacological
considerations mentioned above … hydrogen bond donor or acceptor properties could not be cor…
considerations mentioned above … hydrogen bond donor or acceptor properties could not be cor…
[图书][B] Inorganic biochemistry of iron metabolism: from molecular mechanisms to clinical consequences
RR Crichton, JR Boelaert - 2001 - books.google.com
… ferric iron and transport the ferri-siderophore via a receptor-mediated mechanism into the
microbial cell. The receptors for some of these siderophores were identified genetically as the …
microbial cell. The receptors for some of these siderophores were identified genetically as the …
E-cadherin: Its dysregulation in carcinogenesis and clinical implications
… cellular functions in the context of carcinogenesis as well as its … ) and methionine (M92) from
the acceptor pocket of E-cadherin … Discoidin domain receptor (DDR) 1 is a receptor tyrosine …
the acceptor pocket of E-cadherin … Discoidin domain receptor (DDR) 1 is a receptor tyrosine …
Nuclear receptors PXR and CAR: implications for drug metabolism regulation, pharmacogenomics and beyond
X Chai, S Zeng, W Xie - Expert opinion on drug metabolism & …, 2013 - Taylor & Francis
… Binding of ligands to these receptors results in the recruitment of the co-activators, thereby
… nuclear receptors, pregnane X receptor (PXR) and constitutive androstane receptor (CAR). …
… nuclear receptors, pregnane X receptor (PXR) and constitutive androstane receptor (CAR). …
Fcγ-receptor–mediated trogocytosis impacts mAb-based therapies: historical precedence and recent developments
RP Taylor, MA Lindorfer - Blood, The Journal of the American …, 2015 - ashpublications.org
… cell by cell-surface receptors on the acceptor cell. Secondly, in an energy-requiring process
that includes actin polymerization, membrane remodeling, and signaling, portions of the …
that includes actin polymerization, membrane remodeling, and signaling, portions of the …
Inactivating mutations of G protein-coupled receptors and diseases: structure-function insights and therapeutic implications
YX Tao - Pharmacology & therapeutics, 2006 - Elsevier
… receptor is expressed on the cell surface with normal glycosylation, but lacks ligand binding
and signaling. Of the mutations observed in humans, all the mutant receptors were … receptors …
and signaling. Of the mutations observed in humans, all the mutant receptors were … receptors …
Thyroid disruption: mechanisms and clinical implications in human health [corrected][published erratum appears in ALTERN MED REV 2010 Apr; 15 (1): 58].
L Patrick - Alternative Medicine Review, 2009 - search.ebscohost.com
… T4 metabolism; and (6) alterations of transport across cellular membranes and alteration
of cellular receptors (TSH receptor). Although these mechanisms reter to animal models, the …
of cellular receptors (TSH receptor). Although these mechanisms reter to animal models, the …
[HTML][HTML] The emerging therapeutic potential of nitro fatty acids and other Michael acceptor-containing drugs for the treatment of inflammation and cancer
M Piesche, J Roos, B Kühn, J Fettel… - Frontiers in …, 2020 - frontiersin.org
… are capable of changing target protein function during cell signaling or in biosynthetic
pathways. NFA target proteins include the peroxisome proliferator-activated receptor γ (PPAR-γ), …
pathways. NFA target proteins include the peroxisome proliferator-activated receptor γ (PPAR-γ), …
BCL2 Family of Apoptosis-Related Genes: Functions and Clinical Implications in Cancer
H Thomadaki, A Scorilas - Critical reviews in clinical laboratory …, 2006 - Taylor & Francis
… cell receptor triggering in human T cells, implicating BIM as a mediator of death receptor-independent
activation-induced cell … acceptor protein might be implicated in murine T cell …
activation-induced cell … acceptor protein might be implicated in murine T cell …
The soluble interleukin 6 receptor: mechanisms of production and implications in disease
SA Jones, S Horiuchi, N Topley… - The FASEB …, 2001 - Wiley Online Library
… an agonist for cell types that … of cell types that are responsive to IL-6. This is in contrast to
the function of most soluble cytokine receptors that bind their ligand and antagonize cellular …
the function of most soluble cytokine receptors that bind their ligand and antagonize cellular …