[图书][B] Inorganic biochemistry of iron metabolism: from molecular mechanisms to clinical consequences

RR Crichton, JR Boelaert - 2001 - books.google.com
… ferric iron and transport the ferri-siderophore via a receptor-mediated mechanism into the
microbial cell. The receptors for some of these siderophores were identified genetically as the …

E-cadherin: Its dysregulation in carcinogenesis and clinical implications

SHM Wong, CM Fang, LH Chuah, CO Leong… - Critical reviews in …, 2018 - Elsevier
cellular functions in the context of carcinogenesis as well as its … ) and methionine (M92) from
the acceptor pocket of E-cadherin … Discoidin domain receptor (DDR) 1 is a receptor tyrosine …

Role of P-glycoprotein in pharmacokinetics: clinical implications

JH Lin, M Yamazaki - Clinical pharmacokinetics, 2003 - Springer
… to have a greater impact on limiting cellular uptake of drugs from blood circulation into brain
… of transgenic mdr knockout mice and in vitro cell systems. When applying in vitro and in vivo …

Thyroid disruption: mechanisms and clinical implications in human health [corrected][published erratum appears in ALTERN MED REV 2010 Apr; 15 (1): 58].

L Patrick - Alternative Medicine Review, 2009 - search.ebscohost.com
… T4 metabolism; and (6) alterations of transport across cellular membranes and alteration
of cellular receptors (TSH receptor). Although these mechanisms reter to animal models, the …

BCL2 Family of Apoptosis-Related Genes: Functions and Clinical Implications in Cancer

H Thomadaki, A Scorilas - Critical reviews in clinical laboratory …, 2006 - Taylor & Francis
cell receptor triggering in human T cells, implicating BIM as a mediator of death receptor-independent
activation-induced cellacceptor protein might be implicated in murine T cell

The soluble interleukin 6 receptor: mechanisms of production and implications in disease

SA Jones, S Horiuchi, N Topley… - The FASEB …, 2001 - Wiley Online Library
… an agonist for cell types that … of cell types that are responsive to IL-6. This is in contrast to
the function of most soluble cytokine receptors that bind their ligand and antagonize cellular

Effects of acceptor composition and mechanism of ABCG1-mediated cellular free cholesterol efflux

S Sankaranarayanan, JF Oram, BF Asztalos… - Journal of lipid …, 2009 - ASBMB
… The purpose of the present investigation was to study in detail the role of different acceptors
in mediating cell cholesterol efflux, and in this way to gain further understanding of the …

Inactivating mutations of G protein-coupled receptors and diseases: structure-function insights and therapeutic implications

YX Tao - Pharmacology & therapeutics, 2006 - Elsevier
receptor is expressed on the cell surface with normal glycosylation, but lacks ligand binding
and signaling. Of the mutations observed in humans, all the mutant receptors were … receptors

Peripheral‐type benzodiazepine receptors: Their implication in brain disease

L Veenman, M Gavish - Drug development research, 2000 - Wiley Online Library
… Central-type benzodiazepine receptors (CBRs), which are considered to mediate these …
on the outer cell membranes of neurons. Peripheral-type benzodiazepine receptors (PBRs) are …

The transporter associated with antigen processing: function and implications in human diseases

B Lankat-Buttgereit, R Tampe - Physiological reviews, 2002 - journals.physiology.org
… and induces subsequent export to the cell surface for presentation to T-cell receptors (Fig.
1), any … , the variable region of the bound peptide is monitored by the T-cell receptor (47, 48). …