Comparison of amorphous solid dispersions of spironolactone prepared by spray drying and electrospinning: The influence of the preparation method on the …
E Szabó, P Záhonyi, D Brecska, DL Galata… - Molecular …, 2020 - ACS Publications
… ASDs. Consequently, it is worth focusing on the selection of the appropriate ASD preparation
… The main goal of this work was to compare two different solvent-based ASD preparation …
… The main goal of this work was to compare two different solvent-based ASD preparation …
Melt-based screening method with improved predictability regarding polymer selection for amorphous solid dispersions
C Auch, M Harms, K Mäder - European Journal of Pharmaceutical …, 2018 - Elsevier
… solvent-based screening but good supersaturation as ASD … preparation of solid dispersions
including hot-melt extrusion (HME) and spray-drying (SD). The compilation of marketed ASD …
including hot-melt extrusion (HME) and spray-drying (SD). The compilation of marketed ASD …
Solvent influence on manufacturability, phase behavior and morphology of amorphous solid dispersions prepared via bead coating
E Boel, F Giacomini, G Van den Mooter - European Journal of …, 2021 - Elsevier
… The importance of solvent selection for ASD manufacturing … auspicious alternative
solvent-based ASD preparation method … influence of the solvent on ASDs prepared with bead …
solvent-based ASD preparation method … influence of the solvent on ASDs prepared with bead …
Amorphous active pharmaceutical ingredients in preclinical studies: preparation, characterization, and formulation
K Nagapudi, J Jona - Current Bioactive Compounds, 2008 - ingentaconnect.com
… be performed with organic solvents it is not … ASD is influenced choice of polymer carrier,
API-polymer interactions, the concentration of the polymer to be used, the method of preparation …
API-polymer interactions, the concentration of the polymer to be used, the method of preparation …
Miniaturized screening tools for polymer and process evaluation
Q Hu, N Wyttenbach, K Shiraki, DS Choi - Amorphous solid dispersions …, 2014 - Springer
… ASD screening methods, including solvent casting, solvent shift, … of successful ASD are
designing and preparing complete … to ASD whereas other drugs are not suitable for ASD owing …
designing and preparing complete … to ASD whereas other drugs are not suitable for ASD owing …
[HTML][HTML] High drug loading nanosized amorphous solid dispersion (NASD) with enhanced in vitro solubility and permeability: Benchmarking conventional ASD
GP Andrews, K Qian, E Jacobs, DS Jones… - International Journal of …, 2023 - Elsevier
… and NASD formulations via a continuous organic solvent/… The ASD and NASD formulations
were prepared using the 10 … In addition, although the selection of polymer and drug loading …
were prepared using the 10 … In addition, although the selection of polymer and drug loading …
In Vitro and In Vivo Evaluation of Amorphous Solid Dispersions Generated by Different Bench-Scale Processes, Using Griseofulvin as a Model Compound
PC Chiang, Y Cui, Y Ran, J Lubach, KJ Chou, L Bao… - The AAPS journal, 2013 - Springer
… Lyo ASD preparation followed the procedure listed as follows… in both preparation time and
the degree of solvent removal (1… processes are suitable to generated ASD material for in vivo …
the degree of solvent removal (1… processes are suitable to generated ASD material for in vivo …
Thermodynamic modeling of solvent-impact on phase separation in amorphous solid dispersions during drying
S Dohrn, P Reimer, C Luebbert… - Molecular …, 2020 - ACS Publications
… /water system showed the predicted liquid–liquid phase separation during drying and is
thus regarded as an inappropriate solvent choice for HPMCAS-based ASD preparation by …
thus regarded as an inappropriate solvent choice for HPMCAS-based ASD preparation by …
[HTML][HTML] Physical stability and dissolution of lumefantrine amorphous solid dispersions produced by spray anti-solvent precipitation
SV Bhujbal, V Pathak, DY Zemlyanov, LS Taylor… - Journal of …, 2021 - Elsevier
… In this study, the feasibility of preparing ASDs by an anti-solvent precipitation method was …
low-cost anti-solvent precipitation approach could be an affordable choice to prepare ASDs of …
low-cost anti-solvent precipitation approach could be an affordable choice to prepare ASDs of …
Amorphous solid dispersion using supercritical fluid technology
P Sheth, H Sandhu - Amorphous Solid Dispersions: Theory and Practice, 2014 - Springer
… environmentally safe, is the choice of SCF for processing of … solvents and subsequent
difficulties of removing the solvents … ASD prepared with PVP K 30 using compressed antisolvent …
difficulties of removing the solvents … ASD prepared with PVP K 30 using compressed antisolvent …