Alterations and interactions of subcortical modulatory systems in Alzheimer's disease
… of DA receptors are decreased in AD brain Agonists of M1 receptor and antagonists of M2
receptor alleviate cognitive impairment in a mouse model of AD Binding to opioid receptors is …
receptor alleviate cognitive impairment in a mouse model of AD Binding to opioid receptors is …
The link between anxiety and Alzheimer's disease: critical facts
… ) axis, which further ameliorates the corticosteroid level in blood. … Impairment in synaptic
plasticity and cognitive imbalance in … Citalopram improved psychiatric and cognitive symptoms in …
plasticity and cognitive imbalance in … Citalopram improved psychiatric and cognitive symptoms in …
[HTML][HTML] Is dysregulation of the HPA-axis a core pathophysiology mediating co-morbid depression in neurodegenerative diseases?
… stressors due to impaired or inadequate neural plasticity (16–… and impairment of spatial
memory in the Morris water maze. … to ameliorate the depression-like behavior of female R6/1 HD …
memory in the Morris water maze. … to ameliorate the depression-like behavior of female R6/1 HD …
Abeta1-40-Dependent Signaling Kinase Cascades Are Accelerated by Divalent Iron in Primary Neuronal Cells
E Yavin, F Kuperstein - search.proquest.com
… In 3xTg-AD mice, aberrant tau phosphorylation and paired helical filaments developed in …
differentiation processes, is involved in synaptic plasticity and learning and has been shown to …
differentiation processes, is involved in synaptic plasticity and learning and has been shown to …
[HTML][HTML] … -1, a biflavonoid isolated from cardiocrinum giganteum seeds, improves memory deficits by modulating the cholinergic system in scopolamine-treated mice
RR Zhang, ZX Lin, XY Lu, X Xia, RW Jiang… - Biomedicine & …, 2019 - Elsevier
… tests, were employed to measure the memory ability. The results revealed that the CGY-1
treatment ameliorated memory impairment in the scopolamine-treated mice. To the best of our …
treatment ameliorated memory impairment in the scopolamine-treated mice. To the best of our …
[HTML][HTML] Serotonin 6 receptor controls Alzheimer's disease and depression
HM Yun, KR Park, EC Kim, S Kim, JT Hong - Oncotarget, 2015 - ncbi.nlm.nih.gov
… that administration of SSRIs reduced brain Aβ levels in mice [47–48], and … , citalopram-treated
mice [49]. Furthermore APBA1/2 directly interacted with APP and γ-secretase and impaired …
mice [49]. Furthermore APBA1/2 directly interacted with APP and γ-secretase and impaired …
[HTML][HTML] Uncovering the Early Events Associated with Oligomeric Aβ-Induced Src Activation
SI Mota, L Fão, P Coelho, AC Rego - Antioxidants, 2023 - mdpi.com
… to the loss of synaptic plasticity and cellular demise [2]. … of 15-month-old 3xTg-AD female
mice, both occurring concomitantly … shown to rescue spatial memory deficits, synaptic depletion, …
mice, both occurring concomitantly … shown to rescue spatial memory deficits, synaptic depletion, …
When ageing meets the blues: Are current antidepressants effective in depressed aged patients?
… in ameliorating depression-… mice, whereas acute administration of citalopram and paroxetine
reduced immobility only in wild type mice and no effects were detected in knockout mice, …
reduced immobility only in wild type mice and no effects were detected in knockout mice, …
[HTML][HTML] Understanding how physical exercise improves Alzheimer's disease: cholinergic and monoaminergic systems
B Zong, F Yu, X Zhang, W Zhao, P Sun… - Frontiers in Aging …, 2022 - frontiersin.org
… In the Tg2576 mouse model of AD, dopaminergic neuron … synaptic plasticity and excitability
and contributed to memory and … ameliorate synaptic dysfunction and cognitive decline in AD. …
and contributed to memory and … ameliorate synaptic dysfunction and cognitive decline in AD. …
Recent Progress in the Treatment Strategies for Alzheimer's Disease
… about the incidence of AD in men and women, with some claiming that there are no …
mouse model along with lower levels of histone acetylation and expression of synaptic plasticity …
mouse model along with lower levels of histone acetylation and expression of synaptic plasticity …