Defective oral tolerance promotes nephritogenesis in experimental IgA nephropathy induced by oral immunization.

L Gesualdo, ME Lamm… - Journal of immunology …, 1990 - journals.aai.org
… In this study, we explored the role of oral tolerance and … of IgA nephropathy (IgAN), an
important form of nephritis in … sion of oral tolerance, which otherwise develops after chronic oral

The role of nasal tolerance in a model of IgA nephropathy induced in mice by Sendai virus

A Amore, R Coppo, JG Nedrud, N Sigmund… - Clinical …, 2004 - Elsevier
… on the experimental system, however, oral tolerance can be … of mucosal tolerance apparently
exerts a nephritogenic effect by … Nephritis does not develop in complement-deficient mice …

[HTML][HTML] The role of immune modulation in pathogenesis of IgA nephropathy

S Chang, XK Li - Frontiers in Medicine, 2020 - frontiersin.org
… in people without significant glycosylation defects, as long as … model of gluten-induced
experimental IgA glomerulopathy. … B cells are involved in nephritogenic IgA synthesis in a T-cell-…

Pathogenesis of IgA nephropathy

J Barratt, J Feehally, AC Smith - Seminars in nephrology, 2004 - Elsevier
… unwitting “experiments” in which cadaveric kidneys with mesangial IgA deposits were … a
defective clearance by this route, although it is still possible that a small pool of nephritogenic

Systemic immune response after mucosal immunization in patients with IgA nephropathy

FB Waldo - Journal of clinical immunology, 1992 - Springer
… the formation of potentially nephritogenic immune complexes … that the process of oral tolerance
occurs in healthy humans (… in the hematuria of experimental IgA nephropathy. Lab Invest …

Potential immunopathogenic role of the mucosa–bone marrow axis in IgA nephropathy: insights from animal models

Y Suzuki, Y Tomino - Seminars in nephrology, 2008 - Elsevier
… involved in the generation of nephritogenic IgA will help us explain the … uteroglobin (UG)-deficient
mouse models display a number … of experimental IgAN after oral immunization with …

Oral feeding of renal tubular antigen abrogates interstitial nephritis and renal failure in Brown Norway rats

K Pham, WE Smoyer, DC Archer, F Gabbai, CJ Kelly - Kidney international, 1997 - Elsevier
… GESUALDO L, LAMM ME, EMANCIPATOR SN: Defective oral tolerance promotes
nephritogenesis in experimental IgA nephropathy induced by oral immunization. J Immunol 145:3684…

Experimental model of IgA nephropathy

Y Suzuki, Y Tomino - Recent advances in IgA nephropathy, 2009 - books.google.com
… in the generation of nephritogenic IgA, formation of IgA-IC and their … Defective oral tolerance
promotes nephritogenesis in experimental IgA nephropathy induced by oral immunization

Can a dysregulated mucosal immune system in IgA nephropathy be controlled by tonsillectomy?

R Coppo - Nephrology Dialysis Transplantation, 2010 - academic.oup.com
… the role of defective mucosal tolerance, patients with IgAN … which triggers the production
of nephritogenic IgA. Polymeric … Experimental models of oral immunization induced in mice a …

Animal models of IgA nephropathy: Formulating therapeutic strategies

SN EMANCIPATOR, SR CHINTALACHARUVU… - …, 1997 - Wiley Online Library
… the role that defective clearance plays in IgA nephritogenesis have not … Defective oral
tolerance promotes nephritogenesis in experimental IgA nephropathy induced by oral immunization