Dual role of oxidized LDL on the NF-kappaB signaling pathway

F Robbesyn, R Salvayre, A Negre-Salvayre - Free radical research, 2004 - Taylor & Francis
… mechanisms of activation and inhibition and the potential involvement in atherosclerosis. …
proteolysis tends to eliminate the protection conveyed by NF-kB survival pathway.[86] In …

Inflammation and beyond: new directions and emerging drugs for treating atherosclerosis

MJ Bertrand, JC Tardif - Expert opinion on emerging drugs, 2017 - Taylor & Francis
… , double-blinded study involving 18144 patients who had an … 5-LO inhibitors in atherosclerosis
plaque reduction, although … a P-selectin inhibitor and leukotriene pathway inhibitors, but …

Interactions between nitric oxide and lipid oxidation pathways: implications for vascular disease

VB O'Donnell, BA Freeman - Circulation research, 2001 - Am Heart Assoc
vascular protection or potentiation of inflammatory vascular … and inhibit lipoxygenases,
reactions that would be protective. … atherosclerosis in apoE-deficient mice, and inhibition of 15-…

Prostacyclin in Vascular Diseases–Recent Insights and Future Perspectives–

J Kawabe, F Ushikubi, N Hasebe - Circulation Journal, 2010 - jstage.jst.go.jp
… of vascular diseases, such as thrombosis and atherosclerosis, … inhibitors causing unexpected
adverse effects in patients with … pathways in the vessel wall: Role in atherosclerosis. Med …

[HTML][HTML] The role of the coagulation system in peripheral arterial disease: interactions with the Arterial Wall and its vascular microenvironment and implications for …

G Miceli, MG Basso, G Rizzo, C Pintus… - International Journal of …, 2022 - mdpi.com
… in atherosclerosis genesis and progression could help in choosing the right patients for future
dual pathway inhibition … of TNF seemed to protect from atherosclerotic disease. Moreover, …

Interleukins in atherosclerosis: molecular pathways and therapeutic potential

JH Von der Thüsen, J Kuiper, TJC Van Berkel… - Pharmacological …, 2003 - ASPET
… process in atherogenesis and atherosclerotic plaque erosion, the inhibition of TNFα-…
inhibited the production of TNFα by cultured T lymphocytes in vitro and provided protection

Rho/Rho-associated coiled-coil forming kinase pathway as therapeutic targets for statins in atherosclerosis

N Sawada, JK Liao - Antioxidants & redox signaling, 2014 - liebertpub.com
… to understand how inhibition of Rho/ROCK pathway could … protective effects that mimic
those of statins. These comprise … favorable safety profile than dual ROCK inhibitors. However, …

The role of angiogenesis in coronary artery disease: A double-edged sword: Intraplaque angiogenesis in physiopathology and therapeutic angiogenesis for treatment

W Wu, X Li, G Zuo, J Pu, X Wu… - Current pharmaceutical …, 2018 - ingentaconnect.com
… network within an atherosclerotic plaque permits influx of … pathways, causing retarded
VEGF-A-VEGFR-2 signaling and restricted intraplaque angiogenesis. This may inhibit plaque

Vascular calcification in type-2 diabetes and cardiovascular disease: Integrative roles for OPG, RANKL and TRAIL

E Harper, H Forde, C Davenport, KD Rochfort… - Vascular …, 2016 - Elsevier
disease (and particularly atherosclerosis) will be maintained. … mRNA with simultaneous
inhibition of both OPG and TRAIL, … within the vasculature, thus resulting in a context-specific dual

Protective effects of magnesium lithospermate B against diabetic atherosclerosis via Nrf2-ARE-NQO1 transcriptional pathway

KY Hur, SH Kim, MA Choi, DR Williams, Y Lee… - Atherosclerosis, 2010 - Elsevier
pathway, which plays an important role in inhibition of the major molecular mechanisms that
lead to vascularpathway by LAB could be a new therapeutic strategy to prevent diabetic …