[HTML][HTML] Pharmacological inhibition of Factor XIIa attenuates abdominal aortic aneurysm, reduces atherosclerosis, and stabilizes atherosclerotic plaques
AK Searle, YC Chen, M Wallert… - Thrombosis and …, 2022 - thieme-connect.com
… a novel approach to inhibit atherosclerosis and AAA by treating both … that inhibition of FXIIa
with 3F7 has a protective effect in … Dual inhibition of prothrombotic and inflammatory pathways …
with 3F7 has a protective effect in … Dual inhibition of prothrombotic and inflammatory pathways …
Roles of vascular oxidative stress and nitric oxide in the pathogenesis of atherosclerosis
U Förstermann, N Xia, H Li - Circulation research, 2017 - Am Heart Assoc
… by vascular oxidative stress and inhibited by endothelial NO. … The protective role of Nox4
against atherosclerosis may be … Double knockout (DKO) mice deficient in nNOS and ApoE …
against atherosclerosis may be … Double knockout (DKO) mice deficient in nNOS and ApoE …
Statins protect human aortic smooth muscle cells from inorganic phosphate-induced calcification by restoring Gas6-Axl survival pathway
… disease. It is reported that hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase
inhibitors (statins) inhibited vascular … exhibit various protective effects against atherosclerosis, …
inhibitors (statins) inhibited vascular … exhibit various protective effects against atherosclerosis, …
[HTML][HTML] The role of statins in vascular disease
PE Laws, JI Spark, PA Cowled, RA Fitridge - European journal of vascular …, 2004 - Elsevier
… Cellular pathways inhibited by statins are boxed. … Meta-analysis of randomised,
placebo-controlled double blind trials … all patients with clinically overt atherosclerotic cardiac …
placebo-controlled double blind trials … all patients with clinically overt atherosclerotic cardiac …
Molecular mechanisms of vascular effects of high‐density lipoprotein: alterations in cardiovascular disease
C Besler, TF Lüscher, U Landmesser - EMBO molecular medicine, 2012 - embopress.org
… indicative of a potential protective mechanism (ie increased … ‐related pathway that may lead
to potential pro‐atherosclerotic … patients with CAD led to an inhibition of signalling pathways …
to potential pro‐atherosclerotic … patients with CAD led to an inhibition of signalling pathways …
Dual role of matrix metalloproteinases (matrixins) in intimal thickening and atherosclerotic plaque rupture
AC Newby - Physiological reviews, 2005 - journals.physiology.org
… proteolytic pathways (136). A study of balloon angioplasty to the … in atherosclerotic primates,
a broad spectrum MMP inhibitor was infused into animals for 28 days to achieve inhibitory …
a broad spectrum MMP inhibitor was infused into animals for 28 days to achieve inhibitory …
Actions of “antioxidants” in the protection against atherosclerosis
ME Lönn, JM Dennis, R Stocker - Free Radical Biology and Medicine, 2012 - Elsevier
… of oxidative processes in atherosclerosis and its resulting cardiovascular disease by focusing
… be dissociated from atherosclerosis. ► Antioxidants inhibit atherosclerosis by means other …
… be dissociated from atherosclerosis. ► Antioxidants inhibit atherosclerosis by means other …
Inflammation and atherosclerosis: novel insights into plaque formation and destabilization
G Stoll, M Bendszus - Stroke, 2006 - Am Heart Assoc
… −/− mice reversed this protection and increased atherosclerotic lesion … during atherogenesis
is a double-edged sword with a … 123 inhibited the angiotensin II pathway with irbesartan in …
is a double-edged sword with a … 123 inhibited the angiotensin II pathway with irbesartan in …
[HTML][HTML] Potential dual inhibitors of PCSK-9 and HMG-R from natural sources in cardiovascular risk management
… leading to the arterial atherosclerotic plaque formation. The … It took almost half of a century
after the complex pathway of HMG-R-… a protective effect against atherosclerosis and fatty liver …
after the complex pathway of HMG-R-… a protective effect against atherosclerosis and fatty liver …
Sphingolipids in atherosclerosis and vascular biology
S Chatterjee - Arteriosclerosis, thrombosis, and vascular biology, 1998 - Am Heart Assoc
… Ox-LDL may have a dual role in atherosclerosis. First, low levels of … The inhibition of this
pathway was bypassed by the … 75 In addition, the protective role of trimethylsphingosine of the …
pathway was bypassed by the … 75 In addition, the protective role of trimethylsphingosine of the …