… do not know why two kinds of ERK activity with distinct, dichotomous roles exist after stroke.
… but also by cytokines, and the biological functions of ERK activity induced by growth factors …

… ) used for western blotting were purchased from Cell Signaling Technology (Danvers, MA, …
, we performed systematic analysis of EGFR and its two signal pathways Raf/MAPK/ERK 1/2 …

… Two relatively well characterised kinase signalling pathways … factors known to increase
following stroke, such as glutamate, IL-… that both the MAPK/ERK1/2 and p38/SAPK2 pathways are …

… ERK1/2 is abundant in the adult brain, and its activation can play multiple roles in the activity…
ERK1/2 signaling pathway and a variety of neurological diseases, including stroke, neuro-…

… For quantification, we counted the number of live/dead cells within two sectors per well (at …
of 0.5 mg/kg of U0126 (Cell Signaling Technology) at the beginning of the reperfusion. Control …

… the intervention with CH-I and CBL, the expression of pMEK1/2 in both two groups was …
after stroke. Some evidence has shown that CIRI can activate the MAPK/ERK1/2 signal pathway, …

… used in the treatment of IS in China and have a wide range of therapeutic effects on IS by
regulating multiple targets and signaling pathways. The keywords “ischemia stroke, traditional …

… two forepaws, 2 = hung onto the bar with two forepaws and attempted to climb onto the bar,
3 = hung onto the bar with two … post. The average score across three trials was calculated. …

… After reperfusion, the CBF of two groups almost returned to normal level. The volume of …
Besides, the role of the MAPK/ERK1/2 pathway in ischemic stroke is controversial. Because …

… 1/2 signaling pathway performs multiple regulatory functions … Thrombolytic therapy is the
most effective treatment for stroke … Akt, VEGF, and MAPK/ERK1/2 signaling pathways, mediates …