… effect of coadministration of grapefruit juice with artemether on the activity of some hepatic
drug-metabolising … on the antischistosomal efficacy of artemether in S. mansoni-infected mice. …

… Effect of artemether alone and in combination with grapefruit juice on hepatic drug-metabolising …
Graaf CA, van Boxtel CJ., The effect of grapefruit juice on the time-dependent decline of …

… Effects of grapefruit juice on pharmacokinetics and … of grapefruit juice with a lower dose
(150 mg/kg) of artemether achieved … , which suggests that site of induction is hepatic [92]. This …

… It is well known that grapefruits and grapefruit juice (GFJ) cause clinically important … ginkgo
extract significantly affects the hypoglycemic action of tolbutamide, possibly via a hepatic CYP …

… , dihydroartemisinin, artemether, arteether and artesunate in … and combination treatments.
The potential of these drugs to … , linear or saturable effect of artemisinin hepatic amounts on …

… co administration of grapefruit juice with artemether achieved … effect of the juice on the
pharmacokinetics of artemether [38]. … which suggests that the site of induction is hepatic [119]. This …

… properties on the human drug-metabolising enzyme system. … This showed that liver disease
has no effect on the bioavailability … effect on the bioavailability of co-artemether, a fixed …

… the antiplasmodial effect of XA on P. falciparum, and its effect on rat liver CYP enzymes in …
2000 and 2004: the effect of combination of control methods. Malaria journal, 5(1), 33. …

… Although inter individual variability in drug-metabolising enzymes is well-documented, only
… the level of the small bowel and liver. However, grapefruit juice is an example of an inhibitor …

… that coadministration of grapefruit juice with artemether (150 … of the inhibitory effects of
grapefruit juice on CYP450 and cyt b5. … (ART alone) and group L, M, and H were the combination …