Effects of alcohol and cocaine in a mutant mouse model of predisposition to post-traumatic stress disorder

E Paizanis, M Crotti, A Petit, M Règue… - Frontiers in …, 2020 - frontiersin.org
… in these previous studies, the effect of alcohol or cocaine per se on the basal … predisposition
of VGV mice was associated with an increased propensity for voluntary alcohol or cocaine

[HTML][HTML] Early life stress as a predictor of co-occurring alcohol use disorder and post-traumatic stress disorder

RS Lee, LM Oswald, GS Wand - Alcohol research: current reviews, 2018 - ncbi.nlm.nih.gov
… Preclinical studies have employed animal models of stress to … alcohol intake and withdrawal
severity, with Fkbp5 knockoutpredisposed genetically or epigenetically to PTSD and AUD. …

Epigenetics and memory: causes, consequences and treatments for posttraumatic stress disorder and addiction

CL Pizzimenti, KM Lattal - Genes, Brain and Behavior, 2015 - Wiley Online Library
… of cocaine in mice chronically exposed to cocaine induced … , an effect that is often not captured
in animal models using … during adulthood, may predispose individuals to aberrant stress …

Post-traumatic stress disorder and substance use disorders

ME Roberts, SD Moore, JC Beckham - Stress and Addiction, 2007 - Elsevier
… One model suggests that SUDs predispose individuals to PTSD via the … effects of drugs of
abuse. Future neurobiological animal research will likely aim to refine animal models of PTSD, …

Mechanisms of shared vulnerability to post-traumatic stress disorder and substance use disorders

CE María-Ríos, JD Morrow - Frontiers in Behavioral Neuroscience, 2020 - frontiersin.org
… -medication of anxiety with drugs or alcohol, increased exposure … clinical populations and
animal models are presented to … vulnerability factors that may predispose certain individuals to …

Genetic, molecular, and neurobiological determinants of post-traumatic stress disorder-related behaviour in mice

KL Smith - 2020 - ses.library.usyd.edu.au
… to extend research on a mouse model of PTSD developed by … of these drugs has devastating
effects on both health of an … actually serve as a predisposing risk factor for the development …

Substance abuse, memory, and post-traumatic stress disorder

ME Tipps, JD Raybuck, KM Lattal - Neurobiology of learning and memory, 2014 - Elsevier
… CPP We discuss how nicotine, cocaine, and alcohol may … We focus in particular on the
effects of cocaine, nicotine, and … effects do not occur in β2 nAChR subunit knockout mice, but do …

Neurobehavioral mechanisms of traumatic stress in post-traumatic stress disorder

MD Lapiz-Bluhm, AL Peterson - Behavioral Neurobiology of Stress-related …, 2014 - Springer
… of PTSD through animal models and human imaging studies. Most of the animal models have
… Drug and alcohol use and dependence are associated with PTSD. In the NCS, individuals …

Traumatic Stress-Enhanced Alcohol Drinking: Sex Differences and Animal Model Perspectives

DA Finn, CD Clark, AE Ryabinin - Current Addiction Reports, 2024 - Springer
… the comorbidity of alcohol use disorder (AUD) and post-traumatic stress disorder (… that drugs
against specific molecular targets may only work in a patient population that is predisposed

Pathway and biomarker discovery in a posttraumatic stress disorder mouse model

CY Kao - 2015 - pure.mpg.de
… contribute to an individual’s predisposition to develop PTSD. Studies … Genomic alterations
or mutations are trait biomarkers that can … - To analyze early post-traumatic brain extracellular …