Evaluation of ERBB2 gene status and chromosome 17 anomalies in male breast cancer

RR Fonseca, AR Tomás, S André… - The American journal of …, 2006 - journals.lww.com
… was to evaluate the status of ERBB2 and chromosome 17 numerical abnormalities, using …
FISH) in a series of 50 male patients with breast cancer. To assess their prognostic significance…

Chromosome 17 copy number changes in male breast cancer

MM Lacle, CB Moelans, R Kornegoor, C van der Pol… - Cellular oncology, 2015 - Springer
… This is primarily due to the presence of the ERBB2 oncogene (HER2) on chromosome 17q.
… may result in a misleading HER2 gene status assessment, as described before in FBC [12]. …

Interphase cytogenetic analysis of erbB2 and topollα co‐amplification in invasive breast cancer and polysomy of chromosome 17 in ductal carcinoma in situ

DS Murphy, P McHardy, J Coutts… - … journal of cancer, 1995 - Wiley Online Library
… 2 copies of chromosome 17 and so sections of normal breast can be used to evaluate the …
the unique advantage of directly linking genetic anomalies to histoIogically defined cells in …

Chromosome 17 aneusomy is associated with poor prognostic factors in invasive breast carcinoma

AD Watters, JJ Going, TG Cooke… - Breast cancer research and …, 2003 - Springer
breast cancer were examined to evaluate the frequency of … The majority of chromosomal
anomalies in this study, however… of erbB2 and topoIIalpha co-amplification in invasive breast

[HTML][HTML] Clinical validation of an array CGH test for HER2 status in breast cancer reveals that polysomy 17 is a rare event

IT Yeh, MA Martin, RS Robetorye, AR Bolla… - Modern pathology, 2009 - Elsevier
… artificial chromosome (BAC)-based array CGH to evaluate 97 … Multiple abnormalities were
identified on chromosome 17 by … of whole chromosome 17 is a rare event in breast cancer. …

… 17 in transitional cell carcinoma of the bladder: immunohistochemical study of HER2/neu expression and fish analysis of c-erbB-2 gene and chromosome 17

S Simonetti, R Russo, G Ciancia… - … journal of surgical …, 2009 - journals.sagepub.com
… It is well known that HER2/neu protein overexpression and C-erbB2 gene17 in breast
cancer: its role in IHC protein expression and implication for clinical assessment of IHC status. …

Genetic studies of 457 breast cancers. Clinicopathologic parameters compared with genetic alterations

Y Harada, T Katagiri, I Ito, Y Nakamura, M Emi… - Cancer, 1994 - Wiley Online Library
… study permitted more thorough assessment; we were able to … RFLP markers on human
chromosome 17 by fluorescence in … RFLP markers on human chromosome 8. Genuniics 1992; 13…

Cytogenetic analysis of invasive breast cancer: a study of 27 Asian patients

PH Tan, WO Lui, P Ong, LC Lau, M Tao… - Cancer genetics and …, 2000 - Elsevier
… of relevant tissue blocks for microscopic evaluation. The … abnormalities of chromosome
17 may alter the gene dosage of oncogenes (eg, c-erbB2 on 17q) or tumor-suppressor genes (…

Patterns of allele losses suggest the existence of five distinct regions of LOH on chromosome 17 in breast cancer

R Kirchweger, R Zeillinger… - … journal of cancer, 1994 - Wiley Online Library
… of the evi2, erbB2, thra I, gcsfand ram genes. Data presented … anomalies found on chromosome
17 in our set of breast … work to evaluate their real degree of involvement in breast cancer. …

HER2 in breast cancer: a review and update

U Krishnamurti, JF Silverman - Advances in anatomic pathology, 2014 - journals.lww.com
… of cases, abnormalities in HER2 expression at the gene or protein … incidence of chromosome
17 polysomy in breast carcinoma ranges … ERBB2 amplification in breast cancer analyzed by …