Nonpathogenic colonization with chlamydia in the gastrointestinal tract as oral vaccination for inducing transmucosal protection

L Wang, C Zhu, T Zhang, Q Tian, N Zhang… - Infection and …, 2018 - Am Soc Microbiol
muridarum from inducing hydrosalpinx. The transmucosal protection was dependent on
major histocompatibility complex (MHC) class II (MHC-II) antigen presentation but not MHC …

A chlamydial plasmid-dependent secretion system for the delivery of virulence factors to the host cytosol

L Lei, C Yang, MJ Patton, M Smelkinson, D Dorward… - Mbio, 2021 - Am Soc Microbiol
role of GlgA in chlamydial pathogenesis remains poorly defined, nonisogenic Chlamydia
muridarum strains with GlgA … Expression of GlgA/His fusion protein was induced with isopropyl-…

[HTML][HTML] Efficacy of Pgp3 vaccination for Chlamydia urogenital tract infection depends on its native conformation

B Peng, S Zhong, Y Hua, Q Luo, W Dong… - Frontiers in …, 2022 - frontiersin.org
muridarum vaginal infection induces hydrosalpinx in mice, similar to female fallopian tube …
in chlamydial pathogenesis since Pgp3-deficient C. muridarum failed to induce hydrosalpinx

Chlamydia trachomatis glycogen synthase promotes MAPK-mediated proinflammatory cytokine production via TLR2/TLR4 in THP-1 cells

Z Sun, Y Li, H Chen, L Xie, J Xiao, X Luan, B Peng, Z Li… - Life sciences, 2021 - Elsevier
chlamydial component GlgA is secreted into host cells, we sought to determine whether GlgA
is capable of inducing … A recent study showed that GlgA deficiency reduced hydrosalpinx

Transformation of Chlamydia muridarum reveals a role for Pgp5 in suppression of plasmid-dependent gene expression

Y Liu, C Chen, S Gong, S Hou, M Qi, Q Liu… - Journal of …, 2014 - Am Soc Microbiol
Chlamydia muridarum, which naturally infects mice, can induce hydrosalpinx in mice, a …
chromosomal genes glgA (CTL0167 or CT798 in serovar D of C. trachomatis and TC0181 in C. …

Co-ordinated regulation of pathways controlling chlamydial virulence and stress response

SY Omesi - 2021 - cdr.lib.unc.edu
… served a regulatory role in the expression of pgp3 and glgA, … deficient strain of C.muridarum
was associated with a highly … is associated with failure to induce hydrosalpinx, a condition …

The Chlamydia trachomatis Plasmid Is a Transcriptional Regulator of Chromosomal Genes and a Virulence Factor

JH Carlson, WM Whitmire, DD Crane… - Infection and …, 2008 - Am Soc Microbiol
… from our finding that increased glgA transcript levels are … (30) to conclude that the plasmid
affected the induction or … response that does not result in hydrosalpinx (data not shown). Thus, …

Identification of plasmid-free Chlamydia muridarum organisms using a Pgp3 detection-based immunofluorescence assay

C Chen, G Zhong, L Ren, C Lu, Z Li… - Journal of Microbiology …, 2015 - koreascience.kr
… failed to induce hydrosalpinx in mice [12]. It is now known that the chlamydial plasmid not
only … muridarum organisms expressed both Pgp3 and GlgA. Glycogen accumulation was only …

The Repressor Function of the Chlamydia Late Regulator EUO Is Enhanced by the Plasmid-Encoded Protein Pgp4

Q Zhang, CJ Rosario, LM Sheehan, SM Rizvi… - Journal of …, 2020 - Am Soc Microbiol
… and significantly decreased transcription of glgA, which was … -PCR study with a Chlamydia
muridarum pgp4s strain which … Pgp4 did not induce obvious changes in EUO migration by …

Investigation of the role of tissue transglutaminase (TG2) in the infection by Chlamydia trachomatis: a key player in the metabolic rewiring of the host cell

B Maffei - 2018 - theses.hal.science
… Figure 17: p53 degradation induced by Chlamydia infection modifies … Figure 29: TG2 enhances
hydrosalpinx upon C. … can be used by Chlamydia glycogen synthases GlgA and GlgB to …