[HTML][HTML] Impact of corticosterone treatment on spontaneous seizure frequency and epileptiform activity in mice with chronic epilepsy

OW Castro, VR Santos, RYK Pun, JM McKlveen… - 2012 - journals.plos.org
… that CORT treatment increases epileptiform activity in animals with pre-existing epilepsy, and
Epileptiform activity is associated with greater cognitive disruption and poorer prognosis in …

Seizure-induced activation of the HPA axis increases seizure frequency and comorbid depression-like behaviors

A Hooper, R Paracha, J Maguire - Epilepsy & Behavior, 2018 - Elsevier
… actions of corticosterone, we hypothesized that seizure-… the impact on seizure frequency in
chronically epileptic Gabrd/Crh … High frequency epileptiform activity with a sudden onset and …

[HTML][HTML] Neurosteroids and seizure activity

B Miziak, M Chrościńska-Krawczyk… - Frontiers in …, 2020 - frontiersin.org
… can suppress epileptic seizures, yet they do not affect in any way … the onset of the first
spontaneous seizure. During this time, … (99) examined the impact of ALLO on epileptiform activity

Seizure frequency and cortisol and dehydroepiandrosterone sulfate (DHEAS) levels in women with epilepsy receiving antiepileptic drug treatment

C Andrea Galimberti, F Magri, F Copello… - …, 2005 - Wiley Online Library
… ) and in cortisol levels has been observed in the epileptic postictal … , both spontaneous and
temporal lobe seizures induced by … effects of AED treatment and/or of seizures themselves. …

Stress and corticosteroid modulation of seizures and synaptic inhibition in the hippocampus

N Maggio, M Segal - Experimental neurology, 2012 - Elsevier
… to exacerbation of spontaneous seizures. We have now studied the effects of an acute
stress on reactivity of juvenile rats to kainic acid (KA), which produces epileptic seizures. With a …

[HTML][HTML] Stress and corticosteroids aggravate morphological changes in the dentate gyrus after early-life experimental febrile seizures in mice

JS Van Campen, EVS Hessel, K Bohmbach… - Frontiers in …, 2018 - frontiersin.org
… Therefore, we studied the consequences of ear corticosteroid … We conclude that corticosterone
exposure during early … injection on single cell spontaneous synaptic events (which …

Corticosterone increases spike-wave discharges in a dose-and time-dependent manner in WAG/Rij rats

U Schridde, G van Luijtelaar - Pharmacology Biochemistry and Behavior, 2004 - Elsevier
… systemic effects of different doses of the corticosteroid corticosterone on seizure activity
in a … (1) DBA/2J mice show spontaneous spike-wave spindling episodes (7–8 Hz) in their …

Gonadal, adrenal, and neuroactive steroids' role in ictal activity

ME Rhodes, JP Harney, CA Frye - Brain research, 2004 - Elsevier
… characterizing effects and mechanisms of hormones on ictal activity, … , significantly decreases
seizure frequency compared to … of cortisol are greater among individuals with epilepsy

The acceleration of amygdala kindling epileptogenesis by chronic low-dose corticosterone involves both mineralocorticoid and glucocorticoid receptors

G Kumar, A Couper, TJ O'Brien, MR Salzberg… - …, 2007 - Elsevier
effect of chronic stress, accelerates epileptogenesis in the electrical amygdala kindling rat
model of temporal lobe epilepsy … kainic acid-induced epileptiform activity, an effect reversed by …

[HTML][HTML] Neurosteroids—endogenous regulators of seizure susceptibility and role in the treatment of epilepsy

DS Reddy, MA Rogawski - 2012 - europepmc.org
… state with spontaneous recurrent seizures. … beneficial effect of progesterone in women with
perimenstrual seizure … Along with cortisol, ACTH also enhances the synthesis of adrenal DOC…