… of a new pain target. We believe that animal models can provide unparalleled mechanistic
… , such as chronic pain, and should continue to be used in pain research in combination with …

… We also describe ways in which pain can be avoided or reduced, by reconsidering how …
Ultimately, reducing the pain that animals experience will require scientific innovation paired …

… Incorporating integrated body pose and FTIR data acquisition with machine learning in
multiple unilateral animal pain models shows we can readily capture behavioral features …

… This capability and the possibility of training the software to recognize a greater range of
behaviours, including pain-specific indicators, should be of considerable value for assessing …

… advances will not occur until we follow the description of exciting discoveries with hypothesis
testing using clinically relevant preclinical animal models … trials to innovative study designs …

… Engineering, the Institute of Medicine, and the National Research Council: • Download
hundreds of free books in PDF • Read thousands of books online for free • Explore our innovative …

… of our new model, we processed novel images obtained from animals undergoing a laparotomy
(… Our new model classified an image as either “pain” or “no pain” with an accompanying …

… of the innovations in noninvasive imaging, which are mainly applicable to biomedical
research and testing, and discusses their merits and limitations in relation to animal welfare and …

… animal's welfare, but are currently vastly under-utilized for this purpose. Here, we review
advances … Behaviour is used as a measure of animal welfare because an animal's state can be …

… animal models before they can 'replace' the animal model in … of validation of animal models,
the non-animal technologies are … human-based models that are highly predictive [64, 66]. …