Inoculation stress hypothesis of environmental enrichment

EJ Crofton, Y Zhang, TA Green - Neuroscience & Biobehavioral Reviews, 2015 - Elsevier
… of others studying environmental enrichment using different protocols, this paper outlines
a theory that the mild daily stresses of the enriched lifestyle are adaptive and inoculate rats to …

Therapeutic and protective effect of environmental enrichment against psychogenic and neurogenic stress

C Fox, Z Merali, C Harrison - Behavioural brain research, 2006 - Elsevier
… has been suggested to represent a mechanism of stress inoculation. The … hypotheses.
Future research is necessary to fully elucidate the processes by which environmental enrichment

Differential impact of stress and environmental enrichment on corticolimbic circuits

MA Smail, BL Smith, N Nawreen, JP Herman - … biochemistry and behavior, 2020 - Elsevier
… further consistent with the ‘inoculation stress hypothesis’, suggesting that the variety of
morphological and molecular changes initiated by EE can improve stress resilience (Crofton et al.…

The influence of environmental enrichment on cardiovascular and behavioral responses to social stress

MC Normann, N McNeal, A Dagner, E Ihm… - Psychosomatic …, 2018 - journals.lww.com
… We hypothesize that both EE and re-pairing will reverse the negative cardiovascular
consequences and reduce depressive behaviors associated with deprivation from a socially …

Environmental enrichment confers stress resiliency to social defeat through an infralimbic cortex-dependent neuroanatomical pathway

ML Lehmann, M Herkenham - Journal of Neuroscience, 2011 - Soc Neuroscience
… defeat stress (SD). In the present study, we hypothesized that enrichment before SD can
confer stress … Thus, an inoculation against distressful stimulation was achieved by eustressful …

Early Life Stress Inoculation Effects on Adult Behaviors

OI Akinbo - 2022 - search.proquest.com
… to either environmental enrichment or brief handling “stress” by … voles to either environmental
enrichment continuously or 10 … Here, we hypothesized that stress inoculation via handling …

[HTML][HTML] Environmental enrichment effects after early stress on behavior and functional brain networks in adult rats

H González-Pardo, JL Arias, G Vallejo, NM Conejo - PloS one, 2019 - journals.plos.org
… Some authors have proposed that the benefits of EE on anxiety-like behavior are not
clear, and proposed the ‘stress inoculationhypothesis of EE as a form of chronic mild …

The environmental enrichment model revisited: A translatable paradigm to study the stress of our modern lifestyle

M Rojas‐Carvajal, A Sequeira‐Cordero… - European Journal of …, 2022 - Wiley Online Library
… interaction and sensorimotor stimulation provided by environmental enrichment (EE) exert
several … Based on the inoculation stress hypothesis, chronic exposure to EE will inoculate

Environmental enrichment, prefrontal cortex, stress, and aging of the brain

G Segovia, A Arco, F Mora - Journal of neural transmission, 2009 - Springer
… We also reported that the stress-induced release of dopamine … that environmental enrichment
reduces the reactivity to stress of … We further hypothesize that the positive effects on stress

Hens with benefits: Can environmental enrichment make chickens more resilient to stress?

M Ross, Q Rausch, B Vandenberg, G Mason - Physiology & Behavior, 2020 - Elsevier
… Here, we therefore test the hypothesis that housing with preferred enrichments enhances …
, animals being ‘toughened up or ‘stress inoculated’ through habituation to suddenness or …