Integration of microfluidics in animal in vitro embryo production

MB Wheeler, M Rubessa - MHR: Basic science of reproductive …, 2017 - academic.oup.com
… If we consider the gamete preparation the first step of a robustin vitro embryo production (IVEP)
routine, we can define the IVF as step number two. In general, when we talk about IVF we …

[HTML][HTML] Opportunities involving microfluidics and 3D culture systems to the in vitro embryo production

MAMM Ferraz, GA Ferronato - Animal Reproduction, 2023 - SciELO Brasil
… Next, we explore the integration of 3D culture systems, including the use of biomimetic
scaffolds and organ-on-a-chip platforms, with a particular focus on the oviduct-on-a-chip. Finally, …

Towards the use of microfluidics for individual embryo culture

RL Krisher, MB Wheeler - … , Fertility and Development, 2009 - CSIRO Publishing
… to both human infertility and wildlife conservation (with few embryos often obtained in both
… Thus, it seems clear that the ultimate goal of integrating all the phases of IVP in a step-wise …

Toward culture of single gametes: The development of microfluidic platforms for assisted reproduction

MB Wheeler, EM Walters, DJ Beebe - Theriogenology, 2007 - Elsevier
microfluidic systems for in vitro embryo production (IVP) and … of these animals was not
compromised following embryonic … With the development of the integrated system and dynamic …

Microfluidics for mammalian embryo culture and selection: where do we stand now?

S Le Gac, V Nordhoff - MHR: Basic science of reproductive …, 2017 - academic.oup.com
… Finally, we discuss potential applications of integrated microfluidic platforms for fundamental
… tested on animal models, and mostly murine and bovine embryos (see Table II). Mouse …

Integration of single oocyte trapping, in vitro fertilization and embryo culture in a microwell-structured microfluidic device

C Han, Q Zhang, R Ma, L Xie, T Qiu, L Wang… - Lab on a Chip, 2010 - pubs.rsc.org
microfluidic device that integrates single oocyte trapping, fertilization and subsequent embryo
culture… Fertilization was achieved in the microfluidic devices with similar fertilization rates to …

Handling individual mammalian embryos using microfluidics

IK Glasgow, HC Zeringue, DJ Beebe… - IEEE transactions on …, 2001 - ieeexplore.ieee.org
… and embryo detection is laying the groundwork for integrated … in milk production, growth
rate, disease resistance, animal product … during development to keep pace with the embryo’s …

[HTML][HTML] Understanding and assisting reproduction in wildlife species using microfluidics

S Le Gac, M Ferraz, B Venzac, P Comizzoli - Trends in biotechnology, 2021 - cell.com
Microfluidic devices present a high level of integration which comes in various flavors: (massive)
parallelization potential, the possibility to implement multi-step processes, and the …

[HTML][HTML] A microfluidic system supports single mouse embryo culture leading to full-term development

TC Esteves, F van Rossem, V Nordhoff, S Schlatt… - RSC …, 2013 - pubs.rsc.org
… found in the oviduct, as well as integrated platforms with parallelization potential for single
… help, as well as the animal caretakers at the MPI Münster, for animal work. This research is …

Application of microfluidic technologies to human assisted reproduction

GD Smith, S Takayama - MHR: Basic science of reproductive …, 2017 - academic.oup.com
Microfluidic IVF/CI in animal model studies has also … These proof-of-concept studies in animal
models are the beginning. … If integration of microfluidic IVF/CI or ICSI can reduce laboratory …