Mechanism of Ganshuang granule extract in alleviating N-acetyl-p-aminophenol-induced hepatocellular injury

WU Qiao, YU Pengfei, BI Yanzhen, LI Zhijie, C Yu… - 临床肝胆病杂志, 2021 - lcgdbzz.org
… granule extract can prevent APAP-induced hepatocellular injury through two ways. The first
… the detoxification pathway, which can activate Nrf2 to increase the expression of antioxidant

Thalictrum minus L. ameliorates particulate matter-induced acute lung injury in mice

R Badamjav, L Zhang, D Sonom, YH Wu, JP Kou… - Journal of …, 2021 - Elsevier
… inflammation via activating Nrf2 modulated by AMPK/Akt/GSK3β pathwayIsoorientin
ameliorates APAP-induced hepatotoxicity via activation Nrf2 antioxidative pathway: the involvement

[HTML][HTML] Penehyclidine hydrochloride inhibits renal ischemia/reperfusion-induced acute lung injury by activating the Nrf2 pathway

Z Liu, Y Li, L Yu, Y Chang, J Yu - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
… We also explored the effects of brusatol on the levels of antioxidant enzymes induced by Nrf2
(… Thus, the PHC-induced activation of the Nrf2 pathway may have ameliorated pulmonary …

Ferulic acid and berberine, via Sirt1 and AMPK, may act as cell cleansing promoters of healthy longevity

JJ DiNicolantonio, MF McCarty, SI Assanga… - Open …, 2022 - openheart.bmj.com
… collaborate to promote MB via activating post-translational … induced hepatotoxicity via
Sirt1/Nrf2 antioxidative pathway in … . Sirtuin 3 ameliorates lung senescence and improves type II …

Sasa borealis Ethanol Extract Protects PC12 Neuronal Cells against Oxidative Stress

MH Kang, YJ Ji, YM Han, GY Jang, DH Kim, JH Lee… - Applied Sciences, 2022 - mdpi.com
… levels of an antioxidant-related factor (Nrf2) and enzymes (HO… In this study, the isoorientin
content of SBE was higher than … 2 -induced oxidative stress via activation of the Nrf2 signaling. …

Over 3 decades of research on dietary flavonoid antioxidants and cancer prevention: What have we achieved?

HH Alfa, RRJ Arroo - Phytochemistry reviews, 2019 - Springer
… what we get through our diet, the role of dietary phytochemicals … The idea that dietary
antioxidants may ameliorate a poor … papers report the activation of transcription factor Nrf2 which …

Rooibos tea—in the cross fire of ROS, mitochondrial dysfunction and loss of proteostasis—positioned for healthy aging

C Smit, S De Wet, T Barron, B Loos - Biogerontology, 2023 - Springer
… the role of the antioxidative properties of rooibos and its role … , the flavonoids aspalathin,
isoorientin and orientin reduced … to activate nuclear factor erythroid 2 related factor (NRF2), …

Lemongrass essential oil attenuates perfluorooctane sulfonate-induced jejunal mucosal injury in rat: a histological, immunohistochemical, and biochemical study

AM Shalaby, AM Albakkosh, RH Shalaby… - Microscopy and …, 2023 - academic.oup.com
… The research involved 40 adult male albino rats (180–200 g; 9–11 … of LGEO and PFOS
ameliorated all investigated PFOS-induced … Isoorientin, one of LGEO flavonoids, activates Nrf2

A review of the role of flavonoids in peptic ulcer (2010–2020)

C Serafim, ME Araruna, EA Júnior, M Diniz… - Molecules, 2020 - mdpi.com
… The gastroprotective activity of isoorientin was … Nrf2 plays a significant role in protecting the
gastrointestinal tract from oxidative damage [174]. Nrf2 induces the expression of antioxidant

Modulation of mitochondrial activity by sugarcane (Saccharum officinarum L.) top extract and its bioactive polyphenols: a comprehensive transcriptomics analysis in …

K Iwata, F Ferdousi, Y Arai, H Isoda - Natural Products and Bioprospecting, 2024 - Springer
Isoorientin (ISO, chemically luteolin-6-C-glucoside). We also demonstrated that STEE could
ameliorate … ), facilitating the classification of DEG sets involved in the biological pathways. …