Large-scale serum protein biomarker discovery in Duchenne muscular dystrophy
Y Hathout, E Brody, PR Clemens… - Proceedings of the …, 2015 - National Acad Sciences
… Serum biomarkers in Duchenne muscular dystrophy (DMD) … a large-scale biomarker
discovery was performed on serum … Levels of 1,125 proteins were quantified in serum samples …
discovery was performed on serum … Levels of 1,125 proteins were quantified in serum samples …
Duchenne Muscular Dystrophy: recent advances in protein biomarkers and the clinical application
C Al-Khalili Szigyarto - Expert Review of Proteomics, 2020 - Taylor & Francis
… Early biomarker discovery studies have praised the value of their emerging results, …
The preparation procedures influence the sample composition in terms of the total protein …
The preparation procedures influence the sample composition in terms of the total protein …
Discovery of serum protein biomarkers in the mdx mouse model and cross-species comparison to Duchenne muscular dystrophy patients
Y Hathout, RL Marathi, S Rayavarapu… - Human molecular …, 2014 - academic.oup.com
… mechanism have been discovered by proteomics and genomics studies of dystrophic
muscle tissue in the past few years (27), effort toward large-scale biomarkers discovery in body …
muscle tissue in the past few years (27), effort toward large-scale biomarkers discovery in body …
Tandem mass tag-based serum proteome profiling for biomarker discovery in young duchenne muscular dystrophy boys
… Further examination of serum protein biomarkers using our workflow in presymptomatic
very young DMD patients less than 2 years old might provide further insight into muscle …
very young DMD patients less than 2 years old might provide further insight into muscle …
[HTML][HTML] Identification of novel, therapy-responsive protein biomarkers in a mouse model of Duchenne muscular dystrophy by aptamer-based serum proteomics
AML Coenen-Stass, G McClorey, R Manzano… - Scientific reports, 2015 - nature.com
… This highlights a limitation of biomarker discovery studies in outbred patient populations …
Notably, potential serum protein biomarkers for FSHD were recently identified in an antibody-…
Notably, potential serum protein biomarkers for FSHD were recently identified in an antibody-…
[HTML][HTML] Disease-specific and glucocorticoid-responsive serum biomarkers for Duchenne Muscular Dystrophy
… Hence, the focus of the present study is to refine the list of serum protein biomarkers using a
subset of … Large-scale serum protein biomarker discovery in Duchenne muscular dystrophy. …
subset of … Large-scale serum protein biomarker discovery in Duchenne muscular dystrophy. …
[HTML][HTML] Blood-derived biomarkers correlate with clinical progression in Duchenne muscular dystrophy
K Strandberg, B Ayoglu, A Roos… - Journal of …, 2020 - content.iospress.com
… of proteins in complex biological samples such as blood, resulting in an accelerated biomarker
discovery … Boxplots representing abundance of serum proteins in patients with different …
discovery … Boxplots representing abundance of serum proteins in patients with different …
Emerging proteomic biomarkers of X-linked muscular dystrophy
P Dowling, S Murphy, M Zweyer… - Expert Review of …, 2019 - Taylor & Francis
… used in biomarker research, the proteomics of the dystrophin-… of early childhood is Duchenne
muscular dystrophy, which is … for large-scale screening studies, most proteomic studies of …
muscular dystrophy, which is … for large-scale screening studies, most proteomic studies of …
[HTML][HTML] Discovery of metabolic biomarkers for Duchenne muscular dystrophy within a natural history study
… Serum metabolite profiling in Duchenne muscular dystrophy (DMD) may enable
discovery … Serum samples from 51 DMD patients from a natural history study and 22 age-matched …
discovery … Serum samples from 51 DMD patients from a natural history study and 22 age-matched …
[HTML][HTML] Circulating biomarkers for Duchenne muscular dystrophy
A Aartsma-Rus, P Spitali - Journal of neuromuscular diseases, 2015 - content.iospress.com
… to the launch of the John Walton Muscular Dystrophy Research Centre we would like to cite
… paved the way to biomarker discoveries in Duchenne over time [78]. Serum CK activity has …
… paved the way to biomarker discoveries in Duchenne over time [78]. Serum CK activity has …