Low frequency of NS5A relevant resistance-associated substitutions to Elbasvir among hepatitis C virus genotype 1a in Spain: a cross-sectional study

C Palladino, M Sánchez-Carrillo, I Mate-Cano… - Scientific Reports, 2017 - nature.com
… In this study, we found a low prevalence of NS5A RASs to elbasvir in HCV-GT1a-… NS5A
inhibitor. To our knowledge, this is the first Spanish nationwide survey of the prevalence of NS5A

Prevalence of relevant NS5A resistance-associated substitutions to elbasvir in genotype 1a hepatitis C virus patients in Spain

C Palladino, B Esteban-Cartelle, I Mate-Cano… - … y microbiologia clinica …, 2018 - Elsevier
… A multi-centre, cross-sectional study was conducted on 632 … In this study, we observed a
low prevalence of NS5A RASs to … In conclusion, our data show that, in Spain, among patients …

Epidemic history and baseline resistance to NS5A-specific direct acting drugs of hepatitis C virus in Spain

C Palladino, IJ Ezeonwumelu, I Mate-Cano… - Scientific reports, 2020 - nature.com
… , the prevalence of NS5A resistance-associated substitutions (… among patients infected with
HCV genotype 1a in Spain, (A) … nationwide cross-sectional surveys of NS5A RASs to elbasvir

Hepatitis C virus genotype 1 infection: Prevalence of NS5A and NS5B resistanceassociated substitutions in naïve patients from Argentina

AP Martínez, G García, E Ridruejo… - Journal of medical …, 2019 - Wiley Online Library
… infected with genotype 1 (HCV-1). In this retrospective cross-sectional study, 108 HCV-1-…
In the present study, no association between the presence of RASs in any region and the …

[PDF][PDF] Characterization of NS5A and NS5B resistance-associated substitutions from genotype 1 HCV infected patients in a Portuguese cohort

RAR Brandão - 2018 - run.unl.pt
… -based cross-sectional study accounting for more than 1 600 … Hepatitis C virus is transmitted
exclusively between humans … NIs, tend to exhibit a low prevalence of baseline RASs …

Molecular Epidemiology and Baseline Resistance of Hepatitis C Virus to Direct Acting Antivirals in Croatia

P Simicic, A Slovic, L Radmanic, A Vince… - Pathogens, 2022 - mdpi.com
… RAS is advised before treatment with grazoprevir/elbasvir in patients … , this study analysed
the prevalence of resistance associated … This cross-sectional retrospective study included 300 …

Epidemic history of hepatitis C virus genotypes and subtypes in Portugal

C Palladino, IJ Ezeonwumelu, R Marcelino, V Briz… - Scientific reports, 2018 - nature.com
… The presence of resistance-associated substitutions (RAS) as … A recent nationwide
cross-sectional survey enrolling 1,685 … naïve subjects in Spain 81 but it was significantly lower

Pre-treatment antiviral resistance in Australians with chronic hepatitis C: Prevalence of NS3 and NS5A resistance data in the state of New South Wales

ATL Ong, E Tay, DE Dwyer, J George… - Antiviral …, 2019 - journals.sagepub.com
… A cross-sectional study was performed at a single large … at least one resistance associated
substitution in the NS3 region… genotype-1a infection prior to prescribing elbasvir/grazoprevir. …

Polymorphisms associated with resistance to protease inhibitors in naïve patients infected with hepatitis C virus genotype 1 in Argentina: Low prevalence of Q80K

AP Martínez, ACA Culasso, PS Pérez, V Romano… - Virus research, 2017 - Elsevier
… about the prevalence of resistance-associated substitutions (… cross-sectional study, 103
patients infected with HCV-1 were … that include other viral regions such as NS5A and NS5B in …

Baseline resistance-guided therapy does not enhance the response to interferon-free treatment of HCV infection in real life

…, L Morano, M Delgado, MJ Ríos, C Galera… - Scientific Reports, 2018 - nature.com
… presence of resistance-associated substitutions (RASs). This … The low frequency of baseline
NS5A RASs in Spanish … who are going to be treated with elbasvir 15 , a setting where the …