Mechanisms of key innate immune cells in early-and late-onset preeclampsia

I Aneman, D Pienaar, S Suvakov, TP Simic… - … in immunology, 2020 - frontiersin.org
… of preeclampsia (8). In this review, we will outline mechanisms of key innate immune cells
implicated in the development of preeclampsia and differentiate how these mechanisms are …

[HTML][HTML] Distinct placental molecular processes associated with early-onset and late-onset preeclampsia

Z Ren, Y Gao, Y Gao, G Liang, Q Chen, S Jiang… - Theranostics, 2021 - ncbi.nlm.nih.gov
mechanisms, whereas the late-onset mild preeclampsia may have no placenta-specific causal
factors. A few regulators may be the key … contain both early- and late-onset PE placental …

[HTML][HTML] … of the pathophysiology of immunologic maladaptation related to early-onset preeclampsia and metabolic syndrome related to late-onset preeclampsia

PY Robillard, G Dekker, M Scioscia, S Saito - American journal of obstetrics …, 2022 - Elsevier
… have acquired an immunologic tolerance mechanism. However, … of the innate immune system
in the immunology of … onset of the disease in early- and late-onset types of the disease 62 , …

Comparison of immune‐related gene signatures and immune infiltration features in earlyand lateonset preeclampsia

Q Wu, X Ying, W Yu, H Li, W Wei, X Lin… - The Journal of Gene …, 2024 - Wiley Online Library
… molecular mechanism especially immune-related mechanismsInnate immune system cells
predominately occupy the … on the mechanism, there are still numerous key questions waiting …

Cellular immune responses in the pathophysiology of preeclampsia

D Miller, K Motomura, J Galaz… - Journal of Leukocyte …, 2022 - academic.oup.com
… into the immune cellular mechanisms of preeclampsia and … carry out important functions
as part of the mechanisms of … Tregs compared to late-onset preeclampsia, 53 suggesting …

A leading role for the immune system in the pathophysiology of preeclampsia

E Laresgoiti-Servitje - Journal of leukocyte biology, 2013 - academic.oup.com
… -onset preeclampsia, differences in these mechanisms may … sFlt1 levels differ in early- and
late-onset preeclampsia. sFlt1 … nonspecific or innate immune system are important in normal …

… in the transcriptional profile of peripheral whole blood in early and late-onset preeclampsia: insights into the molecular basis of the phenotype of preeclampsia

T Chaiworapongsa, R Romero, A Whitten… - Journal of perinatal …, 2013 - degruyter.com
… results in elucidating the mechanisms of other disorders [1, 11, … of the mechanism of disease
in early- and late-onset PE. … involved in the innate immune response of neutrophils and …

The role of immune cells and mediators in preeclampsia

E Deer, O Herrock, N Campbell, D Cornelius… - Nature Reviews …, 2023 - nature.com
… of the immune system, activation of innate immune cells and … or late-onset preeclampsia,
depending on whether if develops … In this Review, we outline key immune mechanisms involved …

Single-cell RNA-seq reveals developmental deficiencies in both the placentation and the decidualization in women with late-onset preeclampsia

J Yang, L Gong, Q Liu, H Zhao, Z Wang, X Li… - … in Immunology, 2023 - frontiersin.org
immune cells. These findings improve our understanding of the molecular mechanisms of
PE. … As decidual immune cells play important regulatory roles, we used CellPhoneDB (53) to …

Systemic transcriptome comparison between earlyAnd lateonset preeclampsia shows distinct pathology and novel biomarkers

F Guo, B Zhang, H Yang, Y Fu, Y Wang… - Cell …, 2021 - Wiley Online Library
… Upregulation of innate immune response occurs during normal … important factor to cause
pre-eclampsia, as we discussed above. However, the role and detailed regulatory mechanism