… -κB signaling, enhanced mitochondrial oxidative stress, and activation of autophagic …
apoptosis protein repeat domain; LRR: leucine-rich repeats; MT: targets NLRX1 to the mitochondria …

… domain, NLRBs or neuronal apoptosis inhibitor proteins (NAIPs) have a baculovirus inhibitor
of … NLRX1 dampens type I interferon production, further supporting its link to mitochondria-…

… TLR4 pathway, NLRX1 also blocks the kinase function of the … -1-dependent signaling and
dampens as well NF-κB activation … the center of the mitochondrial pathway of apoptosis and is …

… This mitochondrial dysfunction and oxidative stress led to insulin … NLRX1, the unique member
of NLR with a mitochondrial … mitochondrial arm of the apoptotic pathway. The attenuation of …

… CPT induces death of A549 cells via characteristic of apoptosis … demonstrate that NLRX1
dampens the oxidative stress [27]. … NLRX1, we identified the p53 RE within its promoter using …

… their non-canonical activity. Here we show that … NLRX1 dampens oxidative stress and
apoptosis in tissue injury via control of mitochondrial activity. J Exp Med. 2017; 214 (8): 2405-20. …

… which ultimately can contribute to tissue injury. In this review, … NLRX1 levels induces
mtROS-mediated 468 oxidative stress … ) reduces apoptosis by 517 interfering with mitochondrial …

… death (apoptosis) [1]. Importantly for the purpose of this review, … leading to mitochondrial
fragmentation dampens RLR signaling. … NLRX1 (also known as NOD5), a NLR localizes to the …

… NLRX1 is present in the mitochondrial matrix and widely … apoptosis-associated speck-like
protein containing a CARD (ASC) … that target oxidative stress, including ROS production and …

… To determine the function of NRF1 in the virus‐induced mitochondrial biogenesis, we used
… to produce H2O2, resulting in increased oxidative damage and activation of cell death. The …