Culture conditions affect meiotic regulation in cumulus cell‐enclosed mouse oocytes

SM Downs, AM Mastropolo - Molecular Reproduction and …, 1997 - Wiley Online Library
… In addition, the possible involvement of energy substrates, … as a substrate for the salvage
pathway, which is active over a … meets the unique metabolic demands of the oocyte in question. …

Adenosine metabolism, adenosine kinase, and evolution

J Park, RS Gupta - Adenosine: a key link between metabolism and brain …, 2013 - Springer
adenosine kinase (AdK, ADK, or AK) plays an important role … concentration of adenosine
by modulation of this key enzyme. … role in the purine salvage pathway, also plays an essential …

Cytoophidia: a conserved yet promising mode of enzyme regulation in nucleotide metabolism

Y Yin, H Yu, X Wang, Q Hu, Z Liu, D Luo… - Molecular Biology …, 2024 - Springer
… Notably, the length of cytoophidia in follicle cells of egg chambers … ubiquitin ligase) can
modulate cytoophidium thickness and width … related to metabolic pathways plays a pivotal role in …

[PDF][PDF] Transcriptional and metabolic characterization for optimization of capacitation-in vitro maturation

N Akin - 2023 - researchportal.vub.be
… -oocyte cyclic adenosine monophosphate (cAMP) which is regulated by both somatic
compartments and the oocyterole in many aspects of acquiring oocyte competence and it can be …

Immunosuppressive role of adenosine produced by ectonucleotidases CD39 and CD73 in ovarian cancer, tumor associated macrophages and the host immune …

I Montalbán del Barrio - 2015 - opus.bibliothek.uni-wuerzburg.de
… in the ATP/adenosine ratio modulates the effector function of … cell tumors, which arise from
the oocytes. These tumors are more … of intracellular cyclic adenosine monophosphate (cAMP) …

Lipid droplets and metabolic pathways regulate steroidogenesis in the corpus luteum

H Talbott, JS Davis - The life cycle of the corpus luteum, 2017 - Springer
… Although little is known about the role of fatty acid β-… The Ser-485 site is phosphorylated by
the cyclic AMP-dependent … LH or PKA activators attenuate AMPK activity through modulation

Who is who in adenosine transport

M Pastor-Anglada, S Pérez-Torras - Frontiers in pharmacology, 2018 - frontiersin.org
… of the role of these transporters in modulating adenosine levels. In … However, the oocyte
membrane might show … a putative link between energy metabolism and purinergic regulation of …

Uptake and salvage of hypoxanthine mediates developmental arrest in preimplantation mouse embryos

MK Dienhart, MJ O'Brien, SM Downs - Biology of reproduction, 1997 - academic.oup.com
… -) to confirm a role for hypoxanthine salvage in the purine-… Hypoxanthine, 8-(6-aminohexyl)amino
cyclic AMP, PRPP, … arrest in mouse oocytes by purines: modulation of cAMP levels and …

Metabolic contribution to age-related chromosome missegregation in mammalian oocytes

BP Mihalas, AL Marston, LE Wu, RB Gilchrist - Reproduction, 2024 - rep.bioscientifica.com
… ROS are likely to play a role in modulating cohesin levels, microtubule stability, … Participation
of the adenosine salvage pathway and cyclic AMP modulation in oocyte energy metabolism

Requirement for glucose in ligand-stimulated meiotic maturation of cumulus cell-enclosed mouse oocytes

CF Fagbohun, SM Downs - Reproduction, 1992 - rep.bioscientifica.com
modulation of both the type of energy source and its concentration within culture medium plays
a vital role in the meiotic response of the oocyte … have varied effects on purine metabolism