Polydendrocytes (NG2 cells): multifunctional cells with lineage plasticity

A Nishiyama, M Komitova, R Suzuki… - Nature Reviews …, 2009 - nature.com
… related to the lineage and function of polydendrocytes in the CNS. … These cells have been
known as NG2 cells. However, we have proposed that they should be called polydendrocytes

[HTML][HTML] NG2 cells (polydendrocytes) in brain physiology and repair

A Nishiyama, R Suzuki, X Zhu - Frontiers in neuroscience, 2014 - frontiersin.org
… Thus, lineage restriction of NG2 cells appears to occur gradually during the first few … , NG2
cells in certain regions retain some degree of context-dependent lineage plasticity, which is …

[HTML][HTML] Polydendrocytes display large lineage plasticity following focal cerebral ischemia

P Honsa, H Pivonkova, D Dzamba, M Filipova… - PLoS …, 2012 - journals.plos.org
… In our study we used NG2, as a generally accepted marker of polydendrocytes and,
moreover, this proteoglycan is not down-regulated after injury as in the case of PDGFαR [12]. …

Multipotency and therapeutic potential of NG2 cells

M Valny, P Honsa, J Kriska, M Anderova - Biochemical Pharmacology, 2017 - Elsevier
… about NG2 cells proliferation, their fate plasticity during … as polydendrocytes or oligodendrocyte
precursor cells (OPCs… approaches to treat oligodendrocyte lineage cell (OL) disorders …

NG2 cells: Properties, progeny and origin

J Trotter, K Karram, A Nishiyama - Brain research reviews, 2010 - Elsevier
NG2 cells but first summarise current knowledge regarding the structure and function of the
NG2 protein, the defining feature of this class of cells. … diagram showing the NG2 cell lineage. …

[图书][B] NG2-glia (polydendrocytes)

AM Butt - 2016 - books.google.com
… -glia express oligodendroglial lineage cell markers, first Pdgfra and after a slight delay
NG2, together with transcription factors, such as Sox10 and Olig2, which are necessary and …

Lineage, fate, and fate potential of NG2-glia

A Nishiyama, L Boshans, CM Goncalves, J Wegrzyn… - Brain research, 2016 - Elsevier
… The term polydendrocytes has been … that NG2 cells retain lineage plasticity to some
degree by maintaining partial repressive marks on lineage specific genes, and that this plasticity

Olig2-dependent developmental fate switch of NG2 cells

X Zhu, H Zuo, BJ Maher, DR Serwanski… - …, 2012 - journals.biologists.com
NG2-expressing cells (NG2 cells or polydendrocytes) generate … lineage to astrocytes.
These observations indicate that NG2 cells retain developmental glial lineage plasticity, and that …

Modulation of oligodendrocyte generation during a critical temporal window after NG2 cell division

RA Hill, KD Patel, CM Goncalves, J Grutzendler… - Nature …, 2014 - nature.com
… window of plasticity, the fate of divided NG2 cells is sensitive to … from NG2 cells (also
known as polydendrocytes or … the lineage, as we were focused on the fate of dividing NG2

“Silenced” polydendrocytes: a new cell type within the oligodendrocyte progenitor cell population?

A Hermann, MD Brandt, KF Loewenbrück… - Cell and tissue …, 2010 - Springer
… Finally, besides being progenitor cells throughout adulthood, NG2 cells could also represent
important modulators of neuronal plasticity and excitability, well integrated in local network …