… is essential in vertebrate head formation and … the activity of Tcf3 as a repressor is critical
for head formation, the HMG box DNA-binding domain of Tcf3 was combined with the repressor …

… describes the activities and regulatory modes of TCF/LEF as transcriptional repressors, with
… of TCF7L1 repressor activities in both SO formation, and forebrain progenitor proliferation. …

… of the caudalizing activity gradient in the neurectoderm. … are both orthologs of Tcf3 in other
vertebrates. By RT-PCR analysis, … Hdl and Tcf3b both act as repressors in vivo, and that target …

… contexts during vertebrate embryogenesis, organ and tissue homeostasis, and cancer formation.
… By ablating Tcf3 function, we have uncovered an important requirement for a repressor …

… an essential role during regionalisation of the vertebrate … mesendoderm markers required
for normal brain formation, could … In the zebrafish embryo, loss of Tcf3a repressor activity was …

… family is critical for specification of caudal body formation and erythropoiesis… repressor
complex. These observations introduce a novel mechanism that modulates Tcf3 repressor activity …

… headless/tcf3 mutant has an anterior head defect, which can be rescued by a constitutive
repressor … a Wnt ligand stimulates HIPK2 enzymatic activity during vertebrate gastrulation. Our …

… acts in anterior development and is critical for eye formation. … In non-vertebrates transcriptional
activation and repression is … /Tle co-repressor proteins make a crucial contribution to eye …

… as co-repressors by interacting with histone deacetylases whose activity leads to the … to
TCF, thereby preventing formation of transcription repressor complexes. These findings reveal a …

… To assess if tcf7l2 repressor activity can functionally compensate for loss of tcf7l1a, we …
Repressor activity of headless/Tcf3 is essential for vertebrate head formation. Nature 407:…