Roxadustat for the treatment of anaemia in chronic kidney disease patients not on dialysis: a Phase 3, randomized, open-label, active-controlled study (DOLOMITES)

J Barratt, B Andric, A Tataradze… - Nephrology Dialysis …, 2021 - academic.oup.com
… compared roxadustat versus darbepoetin alfa (DA) in non-dialysis-dependent (NDD) CKD
Roxadustat is a viable option to treat anaemia in NDD CKD patients maintaining Hb levels …

Roxadustat for the treatment of anemia in chronic kidney disease patients not on dialysis: a phase 3, randomized, double-blind, placebo-controlled study (ALPS)

E Shutov, W Sułowicz, C Esposito… - Nephrology Dialysis …, 2021 - academic.oup.com
… , placebo-controlled study examined patients with Stages 3–5 CKD, not on dialysis (NCT01887600).
Patients were randomized (2:1) to oral roxadustat or placebo three times weekly for …

[HTML][HTML] Roxadustat for anemia in patients with kidney disease not receiving dialysis

N Chen, C Hao, X Peng, H Lin, A Yin… - … England Journal of …, 2019 - Mass Medical Soc
… assigned 154 patients with chronic kidney disease in a 2:1 ratio to receive roxadustat or
placebo three times a week for 8 weeks in a double-blind manner. All the patients had a …

A novel scenario in the therapeutic management of anemia of chronic kidney disease: placement and use of roxadustat

F Locatelli, M Ravera, C Esposito, G Grandaliano… - Journal of …, 2024 - Springer
… was reduced in dialysis-dependent-CKD patients treated with roxadustat compared with
erythropoiesis-stimulating agents. Thus, the efficacy of roxadustat is without question, and all …

Iron parameters in patients treated with roxadustat for anemia of chronic kidney disease

T Ganz, F Locatelli, M Arici, T Akizawa… - Journal of Clinical …, 2023 - mdpi.com
… This narrative review describes the effects of roxadustat on iron parameters … in patients with
anemia of non-dialysis-dependent (NDD) or dialysis-dependent (DD) chronic kidney disease

Roxadustat (FG-4592) treatment for anemia in dialysis-dependent (DD) and not dialysis-dependent (NDD) chronic kidney disease patients: A systematic review and …

J Liu, A Zhang, JC Hayden, AS Bhagavathula… - Pharmacological …, 2020 - Elsevier
… receiving the dialysis was unclear. The aim of this study was to evaluate the efficacy of
roxadustat for the treatment of anemia in patients who are dialysis dependent (DD) or dialysis

Roxadustat in the treatment of anaemia in chronic kidney disease

L Del Vecchio, F Locatelli - Expert Opinion on Investigational …, 2018 - Taylor & Francis
… to those treated with roxadustat (mean dose of 1.3 mg/kg, EPO of ∼130 mIU/ml). … during
roxadustat treatment [Citation42]. Sixty incident dialysis patients were all started to roxadustat

Roxadustat treatment of chronic kidney disease-associated anemia in Japanese patients not on dialysis: a phase 2, randomized, double-blind, placebo-controlled trial

T Akizawa, M Iwasaki, T Otsuka, M Reusch… - Advances in Therapy, 2019 - Springer
… –response of roxadustat in Japanese patients with anemia and NDD-CKD. … without rendering
patients functionally or absolutely iron deficient, and 33.8% of patients receiving roxadustat

Oral roxadustat three times weekly in ESA‐naïve and ESA‐converted patients with anemia of chronic kidney disease on hemodialysis: Results from two phase 3 …

T Akizawa, M Ueno, T Shiga… - … Apheresis and Dialysis, 2020 - Wiley Online Library
… 8-week treatment with doses of roxadustat in the same dose range as those used in this
study in patients who were not previously treated with ESA and not dialysis-dependent resulted …

[HTML][HTML] Roxadustat for the treatment of anemia in patients with chronic kidney diseases: a meta-analysis

L Zhang, J Hou, J Li, SS Su, S Xue - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
… ] and whether the patients got dialysis, we performed four subgroup analyses depending
on whether the patient received a high/low dose of roxadustat or whether the patient had NDD/…