Scalable flibanserin nanocrystal-based novel sublingual platform for female hypoactive sexual desire disorder: engineering, optimization adopting the desirability …

MJ Naguib, AIA Makhlouf - Drug Delivery, 2021 - Taylor & Francis
… bioavailability of FLB from the nanocrystal-based sublingual tablets. Based on our findings,
FLB nanocrystal-based sublingual tablets are a promising platform that would increase the …

Pharmacotherapy for female sexual dysfunctions (FSDs): what is on the market and where is this field heading?

RE Nappi, L Tiranini, L Cucinella, E Martini… - Expert Opinion on …, 2023 - Taylor & Francis
… postmenopausal women with a main focus on hypoactive sexual … of flibanserin, and
nanocrystal-based sublingual tablets seem a … The novel combination of bupropion and trazodone …

Spanlastics as a potential platform for enhancing the brain delivery of flibanserin: in vitro response-surface optimization and in vivo pharmacokinetics assessment

WS Alharbi, RH Hareeri, M Bazuhair, MA Alfaleh… - Pharmaceutics, 2022 - mdpi.com
Flibanserin was licensed by the United States Food and Drug Administration (FDA) as an
oral non-hormonal therapy for pre-menopausal women with inhibited sexual … of flibanserin

Nanocrystals and nanosuspensions: an exploration from classic formulations to advanced drug delivery systems

B Rossier, O Jordan, E Allémann… - Drug Delivery and …, 2024 - Springer
sublingual tablets containing flibanserin nanocrystals to treat pre-menopausal hypoactive
sexual desire … The present case study illustrates how via wet milling, a simple and scalable

Development of canagliflozin nanocrystals sublingual tablets in the presence of sodium caprate permeability enhancer: formulation optimization, characterization, in …

S Fathy Elhabal, MA El-Nabarawi, N Abdelaal… - Drug Delivery, 2023 - Taylor & Francis
sublingual tablets. The tablets disintegrated in 51 seconds. The nanocrystal-based sublingual
… Our research suggests that sublingual CFZ nanocrystal-based tablets are a viable drug …

Compritol-based nanostrucutured lipid carriers (NLCs) for augmentation of zolmitriptan bioavailability via the transdermal route: in vitro optimization, ex vivo …

DH Hassan, JN Shohdy, DA El-Setouhy… - Pharmaceutics, 2022 - mdpi.com
… Similar results were declared by Marianne and Amal [83], who prepared flibanserin
nanoparticles utilizing probe sonication for 10 min; however, the prepared formulae maintained its …

[PDF][PDF] of Sublingual Tablets

FA Rahi - iasj.net
Sublingual route of medications is preferred as it easy for patients including old people and
sublingually which are numerous and saliva is efficient for rapid disintegration of sublingual

Flexosomes as a promising nanoplatform for enhancing tolnaftate ocular delivery: Formulation, in vitro characterization, statistical optimization, ex vivo and microbial in …

D Aziz, S Mohamed, S Tayel, A Makhlouf - International Journal of …, 2023 - Elsevier
… Corneas extracted from adult male New Zealand albino rabbits (2.5–3.0 kg) were used in …
In the present work, flexosomes were fashioned as a novel nanosystem for enhanced ocular …

Preparation of Tetrandrine Nanocrystals by Microfluidic Method and Its In Vitro and In Vivo Evaluation

J Huang, S Huang, S Liu, L Feng, W Huang… - AAPS …, 2023 - Springer
The anti-hepatocellular carcinoma effects of TET are acknowledged, but its application is
hindered by its poor water solubility and low bioavailability. Conventional methods for …

Review Article on Superdisintegrants Agents Used in Formulations of Sublingual Tablets.

FA Rahi - Karbala Journal of Pharmaceutical Sciences, 2022 - search.ebscohost.com
Sublingual route of medications is preferred as it easy for patients including old people and
sublingually which are numerous and saliva is efficient for rapid disintegration of sublingual